Christie MJ - Search Results

1

A continuous, fluorescence-based assay of μ-opioid receptor activation in AtT-20 cells.

Knapman A, Santiago M, Du YP, Bennallack PR, Christie MJ, Connor M. Knapman A, et al. Among authors: christie mj. J Biomol Screen. 2013 Mar;18(3):269-76. doi: 10.1177/1087057112461376. Epub 2012 Sep 26. J Biomol Screen. 2013. PMID: 23015017

2

Mu-opioid receptor desensitization: is morphine different?

Connor M, Osborne PB, Christie MJ. Connor M, et al. Among authors: christie mj. Br J Pharmacol. 2004 Nov;143(6):685-96. doi: 10.1038/sj.bjp.0705938. Epub 2004 Oct 25. Br J Pharmacol. 2004. PMID: 15504746 Free PMC article. Review.

3

Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.

Borgland SL, Connor M, Osborne PB, Furness JB, Christie MJ. Borgland SL, et al. Among authors: christie mj. J Biol Chem. 2003 May 23;278(21):18776-84. doi: 10.1074/jbc.M300525200. Epub 2003 Mar 17. J Biol Chem. 2003. PMID: 12642578 Free article.

4

Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine.

Bagley EE, Chieng BC, Christie MJ, Connor M. Bagley EE, et al. Among authors: christie mj. Br J Pharmacol. 2005 Sep;146(1):68-76. doi: 10.1038/sj.bjp.0706315. Br J Pharmacol. 2005. PMID: 15980868 Free PMC article.

5

The role of opioid receptor phosphorylation and trafficking in adaptations to persistent opioid treatment.

Johnson EE, Christie MJ, Connor M. Johnson EE, et al. Among authors: christie mj. Neurosignals. 2005;14(6):290-302. doi: 10.1159/000093044. Neurosignals. 2005. PMID: 16772732 Review.

6

Functional coupling of mu-receptor-Galphai-tethered proteins in AtT20 cells.

Chieng BC, Lee DJ, Du YP, Osborne PB, Christie MJ, Massotte D. Chieng BC, et al. Among authors: christie mj. Neuroreport. 2008 Dec 3;19(18):1793-6. doi: 10.1097/WNR.0b013e3283196b55. Neuroreport. 2008. PMID: 18955903

7

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists.

Gillis A, Gondin AB, Kliewer A, Sanchez J, Lim HD, Alamein C, Manandhar P, Santiago M, Fritzwanker S, Schmiedel F, Katte TA, Reekie T, Grimsey NL, Kassiou M, Kellam B, Krasel C, Halls ML, Connor M, Lane JR, Schulz S, Christie MJ, Canals M. Gillis A, et al. Among authors: christie mj. Sci Signal. 2020 Mar 31;13(625):eaaz3140. doi: 10.1126/scisignal.aaz3140. Sci Signal. 2020. PMID: 32234959

8

Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons.

Borgland SL, Connor M, Ryan RM, Ball HJ, Christie MJ. Borgland SL, et al. Among authors: christie mj. J Physiol. 2002 Mar 1;539(Pt 2):433-44. doi: 10.1113/jphysiol.2001.013322. J Physiol. 2002. PMID: 11882676 Free PMC article.

9

The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.

Chieng B, Connor M, Christie MJ. Chieng B, et al. Among authors: christie mj. Mol Pharmacol. 1996 Sep;50(3):650-5. Mol Pharmacol. 1996. PMID: 8794906

10

Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro.

Connor M, Vaughan CW, Chieng B, Christie MJ. Connor M, et al. Among authors: christie mj. Br J Pharmacol. 1996 Dec;119(8):1614-8. doi: 10.1111/j.1476-5381.1996.tb16080.x. Br J Pharmacol. 1996. PMID: 8982509 Free PMC article.

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