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Page 1
Scaffold-hopping with zwitterionic CCR3 antagonists: identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092.
Bahl A, Barton P, Bowers K, Caffrey MV, Denton R, Gilmour P, Hawley S, Linannen T, Luckhurst CA, Mochel T, Perry MW, Riley RJ, Roe E, Springthorpe B, Stein L, Webborn P. Bahl A, et al. Among authors: mochel t. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6694-9. doi: 10.1016/j.bmcl.2012.08.103. Epub 2012 Sep 11. Bioorg Med Chem Lett. 2012. PMID: 23021991
The discovery of CCR3/H1 dual antagonists with reduced hERG risk.
Bahl A, Barton P, Bowers K, Brough S, Evans R, Luckhurst CA, Mochel T, Perry MW, Rigby A, Riley RJ, Sanganee H, Sisson A, Springthorpe B. Bahl A, et al. Among authors: mochel t. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6688-93. doi: 10.1016/j.bmcl.2012.08.124. Epub 2012 Sep 15. Bioorg Med Chem Lett. 2012. PMID: 23031591
SPINE bioinformatics and data-management aspects of high-throughput structural biology.
Albeck S, Alzari P, Andreini C, Banci L, Berry IM, Bertini I, Cambillau C, Canard B, Carter L, Cohen SX, Diprose JM, Dym O, Esnouf RM, Felder C, Ferron F, Guillemot F, Hamer R, Ben Jelloul M, Laskowski RA, Laurent T, Longhi S, Lopez R, Luchinat C, Malet H, Mochel T, Morris RJ, Moulinier L, Oinn T, Pajon A, Peleg Y, Perrakis A, Poch O, Prilusky J, Rachedi A, Ripp R, Rosato A, Silman I, Stuart DI, Sussman JL, Thierry JC, Thompson JD, Thornton JM, Unger T, Vaughan B, Vranken W, Watson JD, Whamond G, Henrick K. Albeck S, et al. Among authors: mochel t. Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1184-95. doi: 10.1107/S090744490602991X. Epub 2006 Sep 19. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 17001095 Free PMC article. Review.
PipeAlign: A new toolkit for protein family analysis.
Plewniak F, Bianchetti L, Brelivet Y, Carles A, Chalmel F, Lecompte O, Mochel T, Moulinier L, Muller A, Muller J, Prigent V, Ripp R, Thierry JC, Thompson JD, Wicker N, Poch O. Plewniak F, et al. Among authors: mochel t. Nucleic Acids Res. 2003 Jul 1;31(13):3829-32. doi: 10.1093/nar/gkg518. Nucleic Acids Res. 2003. PMID: 12824430 Free PMC article.
[Noninvasive coronary angiography with synchrotron irradiation].
Dix WR, Engelke K, Heuer J, Graeff W, Kupper W, Lohmann M, Makin I, Möchel T, Reumann R. Dix WR, et al. Among authors: mochel t. Biomed Tech (Berl). 1989;34 Suppl:79-80. Biomed Tech (Berl). 1989. PMID: 2819218 German. No abstract available.