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Type I interferons mediate pancreatic toxicities of PERK inhibition.
Yu Q, Zhao B, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY. Yu Q, et al. Among authors: kushner ja. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15420-5. doi: 10.1073/pnas.1516362112. Epub 2015 Dec 1. Proc Natl Acad Sci U S A. 2015. PMID: 26627716 Free PMC article.
Cyclin D2 protein stability is regulated in pancreatic beta-cells.
He LM, Sartori DJ, Teta M, Opare-Addo LM, Rankin MM, Long SY, Diehl JA, Kushner JA. He LM, et al. Among authors: kushner ja. Mol Endocrinol. 2009 Nov;23(11):1865-75. doi: 10.1210/me.2009-0057. Epub 2009 Jul 23. Mol Endocrinol. 2009. PMID: 19628581 Free PMC article.
The diabetes susceptibility gene Clec16a regulates mitophagy.
Soleimanpour SA, Gupta A, Bakay M, Ferrari AM, Groff DN, Fadista J, Spruce LA, Kushner JA, Groop L, Seeholzer SH, Kaufman BA, Hakonarson H, Stoffers DA. Soleimanpour SA, et al. Among authors: kushner ja. Cell. 2014 Jun 19;157(7):1577-90. doi: 10.1016/j.cell.2014.05.016. Cell. 2014. PMID: 24949970 Free PMC article.
Calcineurin signaling regulates human islet {beta}-cell survival.
Soleimanpour SA, Crutchlow MF, Ferrari AM, Raum JC, Groff DN, Rankin MM, Liu C, De León DD, Naji A, Kushner JA, Stoffers DA. Soleimanpour SA, et al. Among authors: kushner ja. J Biol Chem. 2010 Dec 17;285(51):40050-9. doi: 10.1074/jbc.M110.154955. Epub 2010 Oct 13. J Biol Chem. 2010. PMID: 20943662 Free PMC article.
90 results