Chiang WC - Search Results

1

C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress.

Chiang WC, Tishkoff DX, Yang B, Wilson-Grady J, Yu X, Mazer T, Eckersdorff M, Gygi SP, Lombard DB, Hsu AL. Chiang WC, et al. PLoS Genet. 2012 Sep;8(9):e1002948. doi: 10.1371/journal.pgen.1002948. Epub 2012 Sep 13. PLoS Genet. 2012. PMID: 23028355 Free PMC article.

2

Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity.

Ching TT, Chiang WC, Chen CS, Hsu AL. Ching TT, et al. Among authors: chiang wc. Aging Cell. 2011 Jun;10(3):506-19. doi: 10.1111/j.1474-9726.2011.00688.x. Epub 2011 Apr 7. Aging Cell. 2011. PMID: 21348927 Free PMC article.

3

HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity.

Chiang WC, Ching TT, Lee HC, Mousigian C, Hsu AL. Chiang WC, et al. Cell. 2012 Jan 20;148(1-2):322-34. doi: 10.1016/j.cell.2011.12.019. Cell. 2012. PMID: 22265419 Free PMC article.

4

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.

Wei Y, Chiang WC, Sumpter R Jr, Mishra P, Levine B. Wei Y, et al. Among authors: chiang wc. Cell. 2017 Jan 12;168(1-2):224-238.e10. doi: 10.1016/j.cell.2016.11.042. Epub 2016 Dec 22. Cell. 2017. PMID: 28017329 Free PMC article.

5

Mitophagy in aging and longevity.

Guo J, Chiang WC. Guo J, et al. Among authors: chiang wc. IUBMB Life. 2022 Apr;74(4):296-316. doi: 10.1002/iub.2585. Epub 2021 Dec 10. IUBMB Life. 2022. PMID: 34889504 Free article. Review.

6

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Fernández ÁF, Sebti S, Wei Y, Zou Z, Shi M, McMillan KL, He C, Ting T, Liu Y, Chiang WC, Marciano DK, Schiattarella GG, Bhagat G, Moe OW, Hu MC, Levine B. Fernández ÁF, et al. Among authors: chiang wc. Nature. 2018 Jun;558(7708):136-140. doi: 10.1038/s41586-018-0162-7. Epub 2018 May 30. Nature. 2018. PMID: 29849149 Free PMC article.

7

High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding.

Chiang WC, Wei Y, Kuo YC, Wei S, Zhou A, Zou Z, Yehl J, Ranaghan MJ, Skepner A, Bittker JA, Perez JR, Posner BA, Levine B. Chiang WC, et al. ACS Chem Biol. 2018 Aug 17;13(8):2247-2260. doi: 10.1021/acschembio.8b00421. Epub 2018 Jun 21. ACS Chem Biol. 2018. PMID: 29878747 Free PMC article.

8

Author Correction: Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Fernández ÁF, Sebti S, Wei Y, Zou Z, Shi M, McMillan KL, He C, Ting T, Liu Y, Chiang WC, Marciano DK, Schiattarella GG, Bhagat G, Moe OW, Hu MC, Levine B. Fernández ÁF, et al. Among authors: chiang wc. Nature. 2018 Sep;561(7723):E30. doi: 10.1038/s41586-018-0270-4. Nature. 2018. PMID: 29921925

9

Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction.

Dong X, Liang Q, Pan YZ, Wang X, Kuo YC, Chiang WC, Zhang X, Williams NS, Rizo J, Levine B, De Brabander JK. Dong X, et al. Among authors: chiang wc. ACS Med Chem Lett. 2022 Aug 12;13(9):1510-1516. doi: 10.1021/acsmedchemlett.2c00309. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105331 Free PMC article.

10

Beth Levine's Legacy: From the Discovery of BECN1 to Therapies. A Mentees' Perspective.

An Z, Chiang WC, Fernández ÁF, Franco LH, He C, Huang SY, Lee E, Liu Y, Sebti S, Shoji-Kawata S, Sirasanagandla S, Wang RC, Wei Y, Zhao Y, Vega-Rubin-de-Celis S. An Z, et al. Among authors: chiang wc. Front Cell Dev Biol. 2022 Jun 27;10:891332. doi: 10.3389/fcell.2022.891332. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35832792 Free PMC article. Review.

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