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F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.
Oliver JD, Sibley GEM, Beckmann N, Dobb KS, Slater MJ, McEntee L, du Pré S, Livermore J, Bromley MJ, Wiederhold NP, Hope WW, Kennedy AJ, Law D, Birch M. Oliver JD, et al. Among authors: livermore j. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12809-12814. doi: 10.1073/pnas.1608304113. Epub 2016 Oct 25. Proc Natl Acad Sci U S A. 2016. PMID: 27791100 Free PMC article.
Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts.
Howard SJ, Livermore J, Sharp A, Goodwin J, Gregson L, Alastruey-Izquierdo A, Perlin DS, Warn PA, Hope WW. Howard SJ, et al. Among authors: livermore j. Antimicrob Agents Chemother. 2011 Oct;55(10):4880-7. doi: 10.1128/AAC.00621-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807969 Free PMC article.
Pharmacokinetics and pharmacodynamics of fluconazole for cryptococcal meningoencephalitis: implications for antifungal therapy and in vitro susceptibility breakpoints.
Sudan A, Livermore J, Howard SJ, Al-Nakeeb Z, Sharp A, Goodwin J, Gregson L, Warn PA, Felton TW, Perfect JR, Harrison TS, Hope WW. Sudan A, et al. Among authors: livermore j. Antimicrob Agents Chemother. 2013 Jun;57(6):2793-800. doi: 10.1128/AAC.00216-13. Epub 2013 Apr 9. Antimicrob Agents Chemother. 2013. PMID: 23571544 Free PMC article.
Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach.
Warn PA, Livermore J, Howard S, Felton TW, Sharp A, Gregson L, Goodwin J, Petraitiene R, Petraitis V, Cohen-Wolkowiez M, Walsh TJ, Benjamin DK Jr, Hope WW. Warn PA, et al. Among authors: livermore j. Antimicrob Agents Chemother. 2012 Feb;56(2):708-14. doi: 10.1128/AAC.05826-11. Epub 2011 Nov 28. Antimicrob Agents Chemother. 2012. PMID: 22123680 Free PMC article.
Pharmacokinetics and pharmacodynamics of anidulafungin for experimental Candida endophthalmitis: insights into the utility of echinocandins for treatment of a potentially sight-threatening infection.
Livermore JL, Felton TW, Abbott J, Sharp A, Goodwin J, Gregson L, Warn PA, Howard SJ, Hope WW. Livermore JL, et al. Antimicrob Agents Chemother. 2013 Jan;57(1):281-8. doi: 10.1128/AAC.01387-12. Epub 2012 Oct 31. Antimicrob Agents Chemother. 2013. PMID: 23114778 Free PMC article.
Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.
O'Connor L, Livermore J, Sharp AD, Goodwin J, Gregson L, Howard SJ, Felton TW, Schwartz JA, Neely MN, Harrison TS, Perfect JR, Hope WW. O'Connor L, et al. Among authors: livermore j. J Infect Dis. 2013 Jul 15;208(2):351-61. doi: 10.1093/infdis/jit164. Epub 2013 Apr 18. J Infect Dis. 2013. PMID: 23599314 Free PMC article.
57 results