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HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.
Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A. Wang H, et al. Among authors: patel pa. Nucleic Acids Res. 2012 Dec;40(22):11518-30. doi: 10.1093/nar/gks913. Epub 2012 Oct 5. Nucleic Acids Res. 2012. PMID: 23042676 Free PMC article.
The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M. Slaughter A, et al. Among authors: patel pa. Retrovirology. 2014 Nov 25;11:100. doi: 10.1186/s12977-014-0100-1. Retrovirology. 2014. PMID: 25421939 Free PMC article.
The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors.
Feng L, Sharma A, Slaughter A, Jena N, Koh Y, Shkriabai N, Larue RC, Patel PA, Mitsuya H, Kessl JJ, Engelman A, Fuchs JR, Kvaratskhelia M. Feng L, et al. Among authors: patel pa. J Biol Chem. 2013 May 31;288(22):15813-20. doi: 10.1074/jbc.M112.443390. Epub 2013 Apr 24. J Biol Chem. 2013. PMID: 23615903 Free PMC article.
Indole-based allosteric inhibitors of HIV-1 integrase.
Patel PA, Kvaratskhelia N, Mansour Y, Antwi J, Feng L, Koneru P, Kobe MJ, Jena N, Shi G, Mohamed MS, Li C, Kessl JJ, Fuchs JR. Patel PA, et al. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4748-4752. doi: 10.1016/j.bmcl.2016.08.037. Epub 2016 Aug 13. Bioorg Med Chem Lett. 2016. PMID: 27568085 Free PMC article.
Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.
Woodard JL, Huntsman AC, Patel PA, Chai HB, Kanagasabai R, Karmahapatra S, Young AN, Ren Y, Cole MS, Herrera D, Yalowich JC, Kinghorn AD, Burdette JE, Fuchs JR. Woodard JL, et al. Among authors: patel pa. Bioorg Med Chem. 2018 May 15;26(9):2354-2364. doi: 10.1016/j.bmc.2018.03.033. Epub 2018 Mar 23. Bioorg Med Chem. 2018. PMID: 29656990 Free PMC article.
Decline in US-China science: Can ophthalmology remain collaborative?
Huang KY, Patel PA, Huang A, Ho AC, Jonas JB, Sun X, Chen Y, Zheng Y, Tham YC, Weng CY, Wong TY. Huang KY, et al. Among authors: patel pa. Adv Ophthalmol Pract Res. 2024 Nov 6;5(1):13-15. doi: 10.1016/j.aopr.2024.11.002. eCollection 2025 Feb-Mar. Adv Ophthalmol Pract Res. 2024. PMID: 39811832 Free PMC article. No abstract available.
Prevention and Management of Infectious Complications in Pediatric Patients With Cancer: A Survey Assessment of Current Practices Across Children's Oncology Group Institutions.
Slatnick LR, Hoogstra D, Fisher BT, Wolf J, Orgel E, Nessle CN, Patel PA, Miller TP, Wilkes J, Dupuis LL, Goode E, Jackson K, Willis DN, Elgarten C, Aftandilian C, Thompson J, Alexander S, Beauchemin MP, Belsky JA, Hess J, Prudowsky ZD, Guinipero T, Rossoff J, Demedis J, Walsh AM, Richards R, Choi DK, Dvorak CC, Esbenshade AJ. Slatnick LR, et al. Among authors: patel pa. Pediatr Blood Cancer. 2025 Jan 8:e31532. doi: 10.1002/pbc.31532. Online ahead of print. Pediatr Blood Cancer. 2025. PMID: 39780366
Practice Advisory on the Implementation of Preoperative Anemia Management: The Society of Cardiovascular Anesthesiologists and the Society for the Advancement of Patient Blood Management.
Klompas AM, Hensley NB, Burt JM, Grant MC, Guinn NR, Patel PA, Popescu WM, Raphael J, Salenger R, Shore-Lesserson L, Warner MA. Klompas AM, et al. Among authors: patel pa. Anesth Analg. 2024 Nov 22. doi: 10.1213/ANE.0000000000007321. Online ahead of print. Anesth Analg. 2024. PMID: 39671507
427 results