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A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.
Antelo M, Balaguer F, Shia J, Shen Y, Hur K, Moreira L, Cuatrecasas M, Bujanda L, Giraldez MD, Takahashi M, Cabanne A, Barugel ME, Arnold M, Roca EL, Andreu M, Castellvi-Bel S, Llor X, Jover R, Castells A, Boland CR, Goel A. Antelo M, et al. Among authors: goel a. PLoS One. 2012;7(9):e45357. doi: 10.1371/journal.pone.0045357. Epub 2012 Sep 25. PLoS One. 2012. PMID: 23049789 Free PMC article.
Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.
Ricciardiello L, Goel A, Mantovani V, Fiorini T, Fossi S, Chang DK, Lunedei V, Pozzato P, Zagari RM, De Luca L, Fuccio L, Martinelli GN, Roda E, Boland CR, Bazzoli F. Ricciardiello L, et al. Among authors: goel a. Cancer Res. 2003 Feb 15;63(4):787-92. Cancer Res. 2003. PMID: 12591727
3,710 results