Baram J - Search Results

1

Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells.

Drake JC, Baram J, Allegra CJ. Drake JC, et al. Among authors: baram j. Biochem Pharmacol. 1990 Feb 1;39(3):615-8. doi: 10.1016/0006-2952(90)90073-t. Biochem Pharmacol. 1990. PMID: 2306274 No abstract available.

2

Mechanism of leucovorin reversal of methotrexate cytotoxicity in human MCF-7 breast cancer cells.

Boarman DM, Baram J, Allegra CJ. Boarman DM, et al. Among authors: baram j. Biochem Pharmacol. 1990 Dec 15;40(12):2651-60. doi: 10.1016/0006-2952(90)90583-7. Biochem Pharmacol. 1990. PMID: 2260989

3

Mechanism of thymidylate synthase inhibition by methotrexate in human neoplastic cell lines and normal human myeloid progenitor cells.

Chu E, Drake JC, Boarman D, Baram J, Allegra CJ. Chu E, et al. Among authors: baram j. J Biol Chem. 1990 May 25;265(15):8470-8. J Biol Chem. 1990. PMID: 2341391 Free article.

4

Effects on dihydrofolate reductase of methotrexate metabolites and intracellular folates formed following methotrexate exposure of human breast cancer cells.

Drake JC, Allegra CJ, Baram J, Kaufman BT, Chabner BA. Drake JC, et al. Among authors: baram j. Biochem Pharmacol. 1987 Jul 15;36(14):2416-8. doi: 10.1016/0006-2952(87)90612-5. Biochem Pharmacol. 1987. PMID: 2440441 No abstract available.

5

Inhibition of folate-dependent enzymes by 7-OH-methotrexate.

Sholar PW, Baram J, Seither R, Allegra CJ. Sholar PW, et al. Among authors: baram j. Biochem Pharmacol. 1988 Sep 15;37(18):3531-4. doi: 10.1016/0006-2952(88)90709-5. Biochem Pharmacol. 1988. PMID: 2458733 No abstract available.

6

Identification and biochemical properties of 10-formyldihydrofolate, a novel folate found in methotrexate-treated cells.

Baram J, Chabner BA, Drake JC, Fitzhugh AL, Sholar PW, Allegra CJ. Baram J, et al. J Biol Chem. 1988 May 25;263(15):7105-11. J Biol Chem. 1988. PMID: 3366769 Free article.

7

Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.

Allegra CJ, Hoang K, Yeh GC, Drake JC, Baram J. Allegra CJ, et al. Among authors: baram j. J Biol Chem. 1987 Oct 5;262(28):13520-6. J Biol Chem. 1987. PMID: 2443493 Free article.

8

Antifolate metabolism and sites of action: implications for the design of new antifolates.

Fitzhugh AL, Chabner BA, Sholar PW, Baram J, Allegra CJ. Fitzhugh AL, et al. Among authors: baram j. NCI Monogr. 1987;(5):153-7. NCI Monogr. 1987. PMID: 3431590

9

Polyglutamation of methotrexate. Is methotrexate a prodrug?

Chabner BA, Allegra CJ, Curt GA, Clendeninn NJ, Baram J, Koizumi S, Drake JC, Jolivet J. Chabner BA, et al. Among authors: baram j. J Clin Invest. 1985 Sep;76(3):907-12. doi: 10.1172/JCI112088. J Clin Invest. 1985. PMID: 2413074 Free PMC article. Review. No abstract available.

10

Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

Baram J, Allegra CJ, Fine RL, Chabner BA. Baram J, et al. J Clin Invest. 1987 Mar;79(3):692-7. doi: 10.1172/JCI112872. J Clin Invest. 1987. PMID: 3818945 Free PMC article.

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