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Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.
Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV Jr, Walther TC. Wilfling F, et al. Among authors: haas jt. Dev Cell. 2013 Feb 25;24(4):384-99. doi: 10.1016/j.devcel.2013.01.013. Epub 2013 Feb 14. Dev Cell. 2013. PMID: 23415954 Free PMC article.
Lipid droplet biogenesis.
Wilfling F, Haas JT, Walther TC, Farese RV Jr. Wilfling F, et al. Among authors: haas jt. Curr Opin Cell Biol. 2014 Aug;29:39-45. doi: 10.1016/j.ceb.2014.03.008. Epub 2014 Apr 14. Curr Opin Cell Biol. 2014. PMID: 24736091 Free PMC article. Review.
DGAT1 mutation is linked to a congenital diarrheal disorder.
Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV Jr. Haas JT, et al. J Clin Invest. 2012 Dec;122(12):4680-4. doi: 10.1172/JCI64873. Epub 2012 Nov 1. J Clin Invest. 2012. PMID: 23114594 Free PMC article.
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