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Page 1
Crystal structure of the human PRMT5:MEP50 complex.
Antonysamy S, Bonday Z, Campbell RM, Doyle B, Druzina Z, Gheyi T, Han B, Jungheim LN, Qian Y, Rauch C, Russell M, Sauder JM, Wasserman SR, Weichert K, Willard FS, Zhang A, Emtage S. Antonysamy S, et al. Among authors: rauch c. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17960-5. doi: 10.1073/pnas.1209814109. Epub 2012 Oct 15. Proc Natl Acad Sci U S A. 2012. PMID: 23071334 Free PMC article.
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Ho JD, Lee MR, Rauch CT, Aznavour K, Park JS, Luz JG, Antonysamy S, Condon B, Maletic M, Zhang A, Hickey MJ, Hughes NE, Chandrasekhar S, Sloan AV, Gooding K, Harvey A, Yu XP, Kahl SD, Norman BH. Ho JD, et al. Biochim Biophys Acta Gen Subj. 2021 Feb;1865(2):129800. doi: 10.1016/j.bbagen.2020.129800. Epub 2020 Nov 25. Biochim Biophys Acta Gen Subj. 2021. PMID: 33246032
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Maskos K, Fernandez-Catalan C, Huber R, Bourenkov GP, Bartunik H, Ellestad GA, Reddy P, Wolfson MF, Rauch CT, Castner BJ, Davis R, Clarke HR, Petersen M, Fitzner JN, Cerretti DP, March CJ, Paxton RJ, Black RA, Bode W. Maskos K, et al. Among authors: rauch ct. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3408-12. doi: 10.1073/pnas.95.7.3408. Proc Natl Acad Sci U S A. 1998. PMID: 9520379 Free PMC article.
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP. Black RA, et al. Among authors: rauch ct. Nature. 1997 Feb 20;385(6618):729-33. doi: 10.1038/385729a0. Nature. 1997. PMID: 9034190
An essential role for ectodomain shedding in mammalian development.
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA. Peschon JJ, et al. Among authors: rauch ct. Science. 1998 Nov 13;282(5392):1281-4. doi: 10.1126/science.282.5392.1281. Science. 1998. PMID: 9812885
238 results