Dowsett M - Search Results

1

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo.

Martin LA, Pancholi S, Farmer I, Guest S, Ribas R, Weigel MT, Thornhill AM, Ghazoui Z, A'Hern R, Evans DB, Lane HA, Johnston SR, Dowsett M. Martin LA, et al. Among authors: dowsett m. Breast Cancer Res. 2012 Oct 17;14(5):R132. doi: 10.1186/bcr3330. Breast Cancer Res. 2012. PMID: 23075476 Free PMC article.

2

Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention.

Harper-Wynne C, Ross G, Sacks N, Salter J, Nasiri N, Iqbal J, A'Hern R, Dowsett M. Harper-Wynne C, et al. Among authors: dowsett m. Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):614-21. Cancer Epidemiol Biomarkers Prev. 2002. PMID: 12101108 Clinical Trial.

3

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation.

Chan CM, Martin LA, Johnston SR, Ali S, Dowsett M. Chan CM, et al. Among authors: dowsett m. J Steroid Biochem Mol Biol. 2002 Aug;81(4-5):333-41. doi: 10.1016/s0960-0760(02)00074-2. J Steroid Biochem Mol Biol. 2002. PMID: 12361723

4

Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer.

Johnston SR, Head J, Pancholi S, Detre S, Martin LA, Smith IE, Dowsett M. Johnston SR, et al. Among authors: dowsett m. Clin Cancer Res. 2003 Jan;9(1 Pt 2):524S-32S. Clin Cancer Res. 2003. PMID: 12538510 Review.

5

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation.

Martin LA, Farmer I, Johnston SR, Ali S, Marshall C, Dowsett M. Martin LA, et al. Among authors: dowsett m. J Biol Chem. 2003 Aug 15;278(33):30458-68. doi: 10.1074/jbc.M305226200. Epub 2003 May 29. J Biol Chem. 2003. PMID: 12775708 Free article.

6

Mechanisms of resistance to aromatase inhibitors.

Dowsett M, Martin LA, Smith I, Johnston S. Dowsett M, et al. J Steroid Biochem Mol Biol. 2005 May;95(1-5):167-72. doi: 10.1016/j.jsbmb.2005.04.022. J Steroid Biochem Mol Biol. 2005. PMID: 15982868 Review.

7

Aromatase inhibitors: combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance.

Johnston SR, Martin LA, Head J, Smith I, Dowsett M. Johnston SR, et al. Among authors: dowsett m. J Steroid Biochem Mol Biol. 2005 May;95(1-5):173-81. doi: 10.1016/j.jsbmb.2005.04.004. J Steroid Biochem Mol Biol. 2005. PMID: 15996863 Review.

8

Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complex.

Chen B, Gajdos C, Dardes R, Kidwai N, Johnston SR, Dowsett M, Jordan VC. Chen B, et al. Among authors: dowsett m. Int J Oncol. 2005 Aug;27(2):327-35. Int J Oncol. 2005. PMID: 16010412

9

Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation.

Martin LA, Farmer I, Johnston SR, Ali S, Dowsett M. Martin LA, et al. Among authors: dowsett m. Endocr Relat Cancer. 2005 Jul;12 Suppl 1:S75-84. doi: 10.1677/erc.1.01023. Endocr Relat Cancer. 2005. PMID: 16113101

10

Life following aromatase inhibitors--where now for endocrine sequencing?

Johnston SR, Martin LA, Dowsett M. Johnston SR, et al. Among authors: dowsett m. Breast Cancer Res Treat. 2005;93 Suppl 1:S19-25. doi: 10.1007/s10549-005-9038-2. Breast Cancer Res Treat. 2005. PMID: 16247596 Review.

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