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B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.
Farci P, Diaz G, Chen Z, Govindarajan S, Tice A, Agulto L, Pittaluga S, Boon D, Yu C, Engle RE, Haas M, Simon R, Purcell RH, Zamboni F. Farci P, et al. Among authors: purcell rh. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8766-71. doi: 10.1073/pnas.1003854107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421498 Free PMC article.
Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure.
Chen Z, Diaz G, Pollicino T, Zhao H, Engle RE, Schuck P, Shen CH, Zamboni F, Long Z, Kabat J, De Battista D, Bock KW, Moore IN, Wollenberg K, Soto C, Govindarajan S, Kwong PD, Kleiner DE, Purcell RH, Farci P. Chen Z, et al. Among authors: purcell rh. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11369-E11378. doi: 10.1073/pnas.1809028115. Epub 2018 Nov 12. Proc Natl Acad Sci U S A. 2018. PMID: 30420516 Free PMC article.
Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans.
Chen Z, Engle RE, Shen CH, Zhao H, Schuck PW, Danoff EJ, Nguyen H, Nishimura N, Bock KW, Moore IN, Kwong PD, Purcell RH, Govindarajan S, Farci P. Chen Z, et al. Among authors: purcell rh. PLoS Pathog. 2020 Aug 31;16(8):e1008793. doi: 10.1371/journal.ppat.1008793. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32866189 Free PMC article.
In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells.
Sakai A, Takikawa S, Thimme R, Meunier JC, Spangenberg HC, Govindarajan S, Farci P, Emerson SU, Chisari FV, Purcell RH, Bukh J. Sakai A, et al. Among authors: purcell rh. J Virol. 2007 Jul;81(13):7208-19. doi: 10.1128/JVI.01774-06. Epub 2007 Apr 4. J Virol. 2007. PMID: 17409145 Free PMC article.
636 results