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Conjugation of a Ru(II) arene complex to neomycin or to guanidinoneomycin leads to compounds with differential cytotoxicities and accumulation between cancer and normal cells.
Grau-Campistany A, Massaguer A, Carrion-Salip D, Barragán F, Artigas G, López-Senín P, Moreno V, Marchán V. Grau-Campistany A, et al. Among authors: lopez senin p. Mol Pharm. 2013 May 6;10(5):1964-76. doi: 10.1021/mp300723b. Epub 2013 Apr 5. Mol Pharm. 2013. PMID: 23510087 Free article.