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Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes.
Qian Y, Wertheimer SJ, Ahmad M, Cheung AW, Firooznia F, Hamilton MM, Hayden S, Li S, Marcopulos N, McDermott L, Tan J, Yun W, Guo L, Pamidimukkala A, Chen Y, Huang KS, Ramsey GB, Whittard T, Conde-Knape K, Taub R, Rondinone CM, Tilley J, Bolin D. Qian Y, et al. Among authors: li s. J Med Chem. 2011 Apr 14;54(7):2433-46. doi: 10.1021/jm101580m. Epub 2011 Mar 17. J Med Chem. 2011. PMID: 21413799
Consensus repeat domains of E-selectin enhance ligand binding.
Li SH, Burns DK, Rumberger JM, Presky DH, Wilkinson VL, Anostario M Jr, Wolitzky BA, Norton CR, Familletti PC, Kim KJ, et al. Li SH, et al. J Biol Chem. 1994 Feb 11;269(6):4431-7. J Biol Chem. 1994. PMID: 7508442 Free article.
A ligand binding assay for E-selectin.
Anostario M Jr, Li SH, Huang KS. Anostario M Jr, et al. Among authors: li sh. Anal Biochem. 1994 Sep;221(2):317-22. doi: 10.1006/abio.1994.1419. Anal Biochem. 1994. PMID: 7529007
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