Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.
La Motta C, Sartini S, Mugnaini L, Salerno S, Simorini F, Taliani S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Antonioli L, Fornai M, Blandizzi C, Del Tacca M.
La Motta C, et al. Among authors: sartini s.
J Med Chem. 2009 Mar 26;52(6):1681-92. doi: 10.1021/jm801427r.
J Med Chem. 2009.
PMID: 19226143