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Protein kinases of the Hippo pathway: regulation and substrates.
Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR. Avruch J, et al. Among authors: bardeesy n. Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Epub 2012 Aug 9. Semin Cell Dev Biol. 2012. PMID: 22898666 Free PMC article. Review.
Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. Lee JJ, et al. Among authors: bardeesy n. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3091-100. doi: 10.1073/pnas.1411679111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024225 Free PMC article.
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N. Saha SK, et al. Among authors: bardeesy n. Nature. 2014 Sep 4;513(7516):110-4. doi: 10.1038/nature13441. Epub 2014 Jul 2. Nature. 2014. PMID: 25043045 Free PMC article.
YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.
Fitamant J, Kottakis F, Benhamouche S, Tian HS, Chuvin N, Parachoniak CA, Nagle JM, Perera RM, Lapouge M, Deshpande V, Zhu AX, Lai A, Min B, Hoshida Y, Avruch J, Sia D, Campreciós G, McClatchey AI, Llovet JM, Morrissey D, Raj L, Bardeesy N. Fitamant J, et al. Among authors: bardeesy n. Cell Rep. 2015 Mar 17;10(10):1692-1707. doi: 10.1016/j.celrep.2015.02.027. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772357 Free PMC article.
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.
Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, Fitamant J, Ivan M, Kim KS, Broxmeyer HE. Mantel CR, et al. Among authors: bardeesy n. Cell. 2015 Jun 18;161(7):1553-65. doi: 10.1016/j.cell.2015.04.054. Epub 2015 Jun 11. Cell. 2015. PMID: 26073944 Free PMC article.
240 results