Smit MJ - Search Results

1

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.

van Lierop MJ, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH. van Lierop MJ, et al. Among authors: smit mj. PLoS One. 2012;7(11):e48385. doi: 10.1371/journal.pone.0048385. Epub 2012 Nov 12. PLoS One. 2012. PMID: 23152771 Free PMC article.

2

A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor.

van Koppen CJ, Zaman GJ, Timmers CM, Kelder J, Mosselman S, van de Lagemaat R, Smit MJ, Hanssen RG. van Koppen CJ, et al. Among authors: smit mj. Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov;378(5):503-14. doi: 10.1007/s00210-008-0318-3. Epub 2008 Jun 13. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18551279

3

Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol.

Schoonen WG, Kloks CP, Ploemen JP, Horbach GJ, Smit MJ, Zandberg P, Mellema JR, Zuylen CT, Tas AC, van Nesselrooij JH, Vogels JT. Schoonen WG, et al. Among authors: smit mj. Toxicol Sci. 2007 Jul;98(1):271-85. doi: 10.1093/toxsci/kfm076. Epub 2007 Apr 9. Toxicol Sci. 2007. PMID: 17420223

4

Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity.

Schoonen WG, Kloks CP, Ploemen JP, Smit MJ, Zandberg P, Horbach GJ, Mellema JR, Thijssen-Vanzuylen C, Tas AC, van Nesselrooij JH, Vogels JT. Schoonen WG, et al. Among authors: smit mj. Toxicol Sci. 2007 Jul;98(1):286-97. doi: 10.1093/toxsci/kfm077. Epub 2007 Apr 9. Toxicol Sci. 2007. PMID: 17420222

5

Design, synthesis and testing of amino-bicycloaryl based orally bioavailable thrombin inhibitors.

Rewinkel JB, Lucas H, Smit MJ, Noach AB, van Dinther TG, Rood AM, Jenneboer AJ, van Boeckel CA. Rewinkel JB, et al. Among authors: smit mj. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2837-42. doi: 10.1016/s0960-894x(99)00483-7. Bioorg Med Chem Lett. 1999. PMID: 10522702

6

Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration.

Out C, Hageman J, Bloks VW, Gerrits H, Sollewijn Gelpke MD, Bos T, Havinga R, Smit MJ, Kuipers F, Groen AK. Out C, et al. Among authors: smit mj. Hepatology. 2011 Jun;53(6):2075-85. doi: 10.1002/hep.24286. Hepatology. 2011. PMID: 21391220

7

Short- and long-term effects of biliary drainage on hepatic cholesterol metabolism in the rat.

Smit MJ, Temmerman AM, Havinga R, Kuipers F, Vonk RJ. Smit MJ, et al. Biochem J. 1990 Aug 1;269(3):781-8. doi: 10.1042/bj2690781. Biochem J. 1990. PMID: 2390068 Free PMC article.

8

Differences in propionate-induced inhibition of cholesterol and triacylglycerol synthesis between human and rat hepatocytes in primary culture.

Lin Y, Vonk RJ, Slooff MJ, Kuipers F, Smit MJ. Lin Y, et al. Among authors: smit mj. Br J Nutr. 1995 Aug;74(2):197-207. doi: 10.1079/bjn19950123. Br J Nutr. 1995. PMID: 7547837 Free article.

9

Effects of dietary cholesterol on bile formation and hepatic processing of chylomicron remnant cholesterol in the rat.

Smit MJ, Kuipers F, Vonk RJ, Temmerman AM, Jäckle S, Windler EE. Smit MJ, et al. Hepatology. 1993 Mar;17(3):445-54. Hepatology. 1993. PMID: 8444419

10

Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat hepatocytes.

Lin Y, Smit MJ, Havinga R, Verkade HJ, Vonk RJ, Kuipers F. Lin Y, et al. Among authors: smit mj. Biochim Biophys Acta. 1995 Apr 28;1256(1):88-96. doi: 10.1016/0005-2760(95)00006-x. Biochim Biophys Acta. 1995. PMID: 7742360

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