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The TNF alpha converting enzyme (TACE/ADAM17) is expressed in the atherosclerotic lesions of apolipoprotein E-deficient mice: possible contribution to elevated plasma levels of soluble TNF alpha receptors.
Canault M, Peiretti F, Kopp F, Bonardo B, Bonzi MF, Coudeyre JC, Alessi MC, Juhan-Vague I, Nalbone G. Canault M, et al. Among authors: bonardo b. Atherosclerosis. 2006 Jul;187(1):82-91. doi: 10.1016/j.atherosclerosis.2005.08.031. Epub 2005 Oct 7. Atherosclerosis. 2006. PMID: 16214147
HDLs activate ADAM17-dependent shedding.
Tellier E, Canault M, Poggi M, Bonardo B, Nicolay A, Alessi MC, Nalbone G, Peiretti F. Tellier E, et al. Among authors: bonardo b. J Cell Physiol. 2008 Mar;214(3):687-93. doi: 10.1002/jcp.21265. J Cell Physiol. 2008. PMID: 17786981
Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1.
Canault M, Leroyer AS, Peiretti F, Lesèche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G. Canault M, et al. Among authors: bonardo b. Am J Pathol. 2007 Nov;171(5):1713-23. doi: 10.2353/ajpath.2007.070021. Epub 2007 Sep 14. Am J Pathol. 2007. PMID: 17872973 Free PMC article.
The paired basic amino acid-cleaving enzyme 4 (PACE4) is involved in the maturation of insulin receptor isoform B: an opportunity to reduce the specific insulin receptor-dependent effects of insulin-like growth factor 2 (IGF2).
Kara I, Poggi M, Bonardo B, Govers R, Landrier JF, Tian S, Leibiger I, Day R, Creemers JW, Peiretti F. Kara I, et al. Among authors: bonardo b. J Biol Chem. 2015 Jan 30;290(5):2812-21. doi: 10.1074/jbc.M114.592543. Epub 2014 Dec 19. J Biol Chem. 2015. PMID: 25527501 Free PMC article.
The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
Meakin PJ, Mezzapesa A, Benabou E, Haas ME, Bonardo B, Grino M, Brunel JM, Desbois-Mouthon C, Biddinger SB, Govers R, Ashford MLJ, Peiretti F. Meakin PJ, et al. Among authors: bonardo b. Nat Commun. 2018 Apr 3;9(1):1306. doi: 10.1038/s41467-018-03755-2. Nat Commun. 2018. PMID: 29610518 Free PMC article.
25 results