Lozach O - Search Results

1

Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.

Marhadour S, Marchand P, Pagniez F, Bazin MA, Picot C, Lozach O, Ruchaud S, Antoine M, Meijer L, Rachidi N, Le Pape P. Marhadour S, et al. Among authors: lozach o. Eur J Med Chem. 2012 Dec;58:543-56. doi: 10.1016/j.ejmech.2012.10.048. Epub 2012 Nov 2. Eur J Med Chem. 2012. PMID: 23164660

2

Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.

Routier S, Mérour JY, Dias N, Lansiaux A, Bailly C, Lozach O, Meijer L. Routier S, et al. Among authors: lozach o. J Med Chem. 2006 Jan 26;49(2):789-99. doi: 10.1021/jm050945x. J Med Chem. 2006. PMID: 16420063

3

Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3Kα inhibitors.

Bruel A, Logé C, Tauzia ML, Ravache M, Le Guevel R, Guillouzo C, Lohier JF, Oliveira Santos JS, Lozach O, Meijer L, Ruchaud S, Bénédetti H, Robert JM. Bruel A, et al. Among authors: lozach o. Eur J Med Chem. 2012 Nov;57:225-33. doi: 10.1016/j.ejmech.2012.09.001. Epub 2012 Sep 10. Eur J Med Chem. 2012. PMID: 23063566

4

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors.

Loidreau Y, Marchand P, Dubouilh-Benard C, Nourrisson MR, Duflos M, Lozach O, Loaëc N, Meijer L, Besson T. Loidreau Y, et al. Among authors: lozach o. Eur J Med Chem. 2012 Dec;58:171-83. doi: 10.1016/j.ejmech.2012.10.006. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124214

5

Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.

Abadi AH, Abou-Seri SM, Abdel-Rahman DE, Klein C, Lozach O, Meijer L. Abadi AH, et al. Among authors: lozach o. Eur J Med Chem. 2006 Mar;41(3):296-305. doi: 10.1016/j.ejmech.2005.12.004. Epub 2006 Feb 21. Eur J Med Chem. 2006. PMID: 16494969

6

Synthesis of novel 5-substituted indirubins as protein kinases inhibitors.

Beauchard A, Ferandin Y, Frère S, Lozach O, Blairvacq M, Meijer L, Thiéry V, Besson T. Beauchard A, et al. Among authors: lozach o. Bioorg Med Chem. 2006 Sep 15;14(18):6434-43. doi: 10.1016/j.bmc.2006.05.036. Epub 2006 Jun 8. Bioorg Med Chem. 2006. PMID: 16759872

7

Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: synthesis, biological evaluation and molecular modeling studies.

Logé C, Testard A, Thiéry V, Lozach O, Blairvacq M, Robert JM, Meijer L, Besson T. Logé C, et al. Among authors: lozach o. Eur J Med Chem. 2008 Jul;43(7):1469-77. doi: 10.1016/j.ejmech.2007.09.020. Epub 2007 Sep 29. Eur J Med Chem. 2008. PMID: 17981370

8

Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents.

Jacquemard U, Dias N, Lansiaux A, Bailly C, Logé C, Robert JM, Lozach O, Meijer L, Mérour JY, Routier S. Jacquemard U, et al. Among authors: lozach o. Bioorg Med Chem. 2008 May 1;16(9):4932-53. doi: 10.1016/j.bmc.2008.03.034. Epub 2008 Mar 17. Bioorg Med Chem. 2008. PMID: 18439832

9

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Debdab M, Renault S, Lozach O, Meijer L, Paquin L, Carreaux F, Bazureau JP. Debdab M, et al. Among authors: lozach o. Eur J Med Chem. 2010 Feb;45(2):805-10. doi: 10.1016/j.ejmech.2009.10.009. Epub 2009 Oct 12. Eur J Med Chem. 2010. PMID: 19879673

10

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.

Giraud F, Alves G, Debiton E, Nauton L, Théry V, Durieu E, Ferandin Y, Lozach O, Meijer L, Anizon F, Pereira E, Moreau P. Giraud F, et al. Among authors: lozach o. J Med Chem. 2011 Jul 14;54(13):4474-89. doi: 10.1021/jm200464w. Epub 2011 Jun 10. J Med Chem. 2011. PMID: 21623630

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