Wang M - Search Results

1

Tissue bioanalysis of biotherapeutics and drug targets to support PK/PD.

Neubert H, Fountain S, King L, Clark T, Weng Y, O'Hara DM, Li W, Leung S, Ray C, Palandra J, Ocaña MF, Chen J, Ji C, Wang M, Long K, Gorovits B, Fluhler E. Neubert H, et al. Among authors: wang m. Bioanalysis. 2012 Nov;4(21):2589-604. doi: 10.4155/bio.12.234. Bioanalysis. 2012. PMID: 23173794 Review.

2

One mouse, one pharmacokinetic profile: quantitative whole blood serial sampling for biotherapeutics.

Joyce AP, Wang M, Lawrence-Henderson R, Filliettaz C, Leung SS, Xu X, O'Hara DM. Joyce AP, et al. Among authors: wang m. Pharm Res. 2014 Jul;31(7):1823-33. doi: 10.1007/s11095-013-1286-y. Epub 2014 Jan 24. Pharm Res. 2014. PMID: 24464271

3

Tissue expression profile of human neonatal Fc receptor (FcRn) in Tg32 transgenic mice.

Fan YY, Avery LB, Wang M, O'Hara DM, Leung S, Neubert H. Fan YY, et al. Among authors: wang m. MAbs. 2016 Jul;8(5):848-53. doi: 10.1080/19420862.2016.1178436. Epub 2016 Apr 22. MAbs. 2016. PMID: 27104806 Free PMC article.

4

Quantitative biodistribution of biotherapeutics at whole body, organ and cellular levels by autoradiography.

Wang M, Zhan Y, O'Neil SP, Harris S, Henson C, McEwen A, Webster R, O'Hara DM. Wang M, et al. Bioanalysis. 2018 Sep 1;10(18):1487-1500. doi: 10.4155/bio-2018-0046. Epub 2018 Sep 10. Bioanalysis. 2018. PMID: 30198746

5

Human FcRn Tissue Expression Profile and Half-Life in PBMCs.

Fan YY, Farrokhi V, Caiazzo T, Wang M, O'Hara DM, Neubert H. Fan YY, et al. Among authors: wang m. Biomolecules. 2019 Aug 15;9(8):373. doi: 10.3390/biom9080373. Biomolecules. 2019. PMID: 31443181 Free PMC article.

6

Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.

Wang M, Kussrow AK, Ocana MF, Chabot JR, Lepsy CS, Bornhop DJ, O'Hara DM. Wang M, et al. Br J Pharmacol. 2017 Jan;174(1):70-81. doi: 10.1111/bph.13654. Epub 2016 Nov 30. Br J Pharmacol. 2017. PMID: 27760281 Free PMC article.

7

Comparison of succinimidyl [(125)I]iodobenzoate with iodogen iodination methods to study pharmacokinetics and ADME of biotherapeutics.

Chen J, Wang M, Joyce A, DeFranco D, Kavosi M, Xu X, O'Hara DM. Chen J, et al. Among authors: wang m. Pharm Res. 2014 Oct;31(10):2810-21. doi: 10.1007/s11095-014-1378-3. Epub 2014 May 21. Pharm Res. 2014. PMID: 24844406

8

Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies.

Avery LB, Wang M, Kavosi MS, Joyce A, Kurz JC, Fan YY, Dowty ME, Zhang M, Zhang Y, Cheng A, Hua F, Jones HM, Neubert H, Polzer RJ, O'Hara DM. Avery LB, et al. Among authors: wang m. MAbs. 2016 Aug-Sep;8(6):1064-78. doi: 10.1080/19420862.2016.1193660. Epub 2016 May 27. MAbs. 2016. PMID: 27232760 Free PMC article.

9

Understanding Lung Deposition of Alpha-1 Antitrypsin in Acute Experimental Mouse Lung Injury Model Using Fluorescence Microscopy.

Wang M, Zhan Y, Chen J, Rong H, O'Neil SP, Ghosh B, Nguyen V, Owens J, Li X, O'Hara DM. Wang M, et al. Int J Mol Imaging. 2016;2016:5768312. doi: 10.1155/2016/5768312. Epub 2016 Dec 6. Int J Mol Imaging. 2016. PMID: 28050284 Free PMC article.

10

Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance.

Wang M, Ishino T, Joyce A, Tam A, Duan W, Lin L, Somers WS, Kriz R, O'Hara DM. Wang M, et al. J Biosci Bioeng. 2015 Jun;119(6):657-60. doi: 10.1016/j.jbiosc.2014.11.008. Epub 2015 Jan 6. J Biosci Bioeng. 2015. PMID: 25575972

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