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In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products.
Devraj R, Williams HD, Warren DB, Mullertz A, Porter CJ, Pouton CW. Devraj R, et al. Among authors: pouton cw. Int J Pharm. 2013 Jan 30;441(1-2):323-33. doi: 10.1016/j.ijpharm.2012.11.024. Epub 2012 Nov 23. Int J Pharm. 2013. PMID: 23178598
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations.
Williams HD, Sassene P, Kleberg K, Bakala-N'Goma JC, Calderone M, Jannin V, Igonin A, Partheil A, Marchaud D, Jule E, Vertommen J, Maio M, Blundell R, Benameur H, Carrière F, Müllertz A, Porter CJ, Pouton CW. Williams HD, et al. Among authors: pouton cw. J Pharm Sci. 2012 Sep;101(9):3360-80. doi: 10.1002/jps.23205. Epub 2012 May 29. J Pharm Sci. 2012. PMID: 22644939
173 results