New LS - Search Results

1

Optimizing hollow-fiber-based pharmacokinetic assay via chemical stability study to account for inaccurate simulated drug clearance of rifampicin.

New LS, Lim TP, Oh JW, Cheah GJ, Kwa AL, Chan EC. New LS, et al. Anal Bioanal Chem. 2013 Feb;405(4):1407-15. doi: 10.1007/s00216-012-6549-7. Epub 2012 Nov 24. Anal Bioanal Chem. 2013. PMID: 23180085

2

Ultra-high performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOFMS) for time-dependent profiling of raw and steamed Panax notoginseng.

Toh DF, New LS, Koh HL, Chan EC. Toh DF, et al. Among authors: new ls. J Pharm Biomed Anal. 2010 May 1;52(1):43-50. doi: 10.1016/j.jpba.2009.12.005. Epub 2009 Dec 22. J Pharm Biomed Anal. 2010. PMID: 20079593

3

Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity.

Saha S, New LS, Ho HK, Chui WK, Chan EC. Saha S, et al. Among authors: new ls. Toxicol Lett. 2010 Feb 1;192(2):141-9. doi: 10.1016/j.toxlet.2009.10.014. Epub 2009 Oct 23. Toxicol Lett. 2010. PMID: 19854250

4

Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.

Teng WC, Oh JW, New LS, Wahlin MD, Nelson SD, Ho HK, Chan EC. Teng WC, et al. Among authors: new ls. Mol Pharmacol. 2010 Oct;78(4):693-703. doi: 10.1124/mol.110.065839. Epub 2010 Jul 12. Mol Pharmacol. 2010. PMID: 20624855

5

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation.

Chan CY, New LS, Ho HK, Chan EC. Chan CY, et al. Among authors: new ls. Toxicol Lett. 2011 Oct 30;206(3):314-24. doi: 10.1016/j.toxlet.2011.07.019. Epub 2011 Aug 5. Toxicol Lett. 2011. PMID: 21839818

6

Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes.

Saha S, New LS, Ho HK, Chui WK, Chan EC. Saha S, et al. Among authors: new ls. Toxicol Lett. 2010 Jun 2;195(2-3):135-41. doi: 10.1016/j.toxlet.2010.03.010. Epub 2010 Mar 20. Toxicol Lett. 2010. PMID: 20307632

7

Interaction of lapatinib with cytochrome P450 3A5.

Chan EC, New LS, Chua TB, Yap CW, Ho HK, Nelson SD. Chan EC, et al. Among authors: new ls. Drug Metab Dispos. 2012 Jul;40(7):1414-22. doi: 10.1124/dmd.112.044958. Epub 2012 Apr 17. Drug Metab Dispos. 2012. PMID: 22511346

8

Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties.

Saha S, Chan DS, Lee CY, Wong W, New LS, Chui WK, Yap CW, Chan EC, Ho HK. Saha S, et al. Among authors: new ls. Eur J Pharmacol. 2012 Dec 15;697(1-3):13-23. doi: 10.1016/j.ejphar.2012.09.021. Epub 2012 Oct 4. Eur J Pharmacol. 2012. PMID: 23041271

9

Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.

Takakusa H, Wahlin MD, Zhao C, Hanson KL, New LS, Chan EC, Nelson SD. Takakusa H, et al. Among authors: new ls. Drug Metab Dispos. 2011 Jun;39(6):1022-30. doi: 10.1124/dmd.110.037531. Epub 2011 Mar 1. Drug Metab Dispos. 2011. PMID: 21363997 Free PMC article.

10

Distribution study of orally administered lipoic acid in rat brain tissues.

Chng HT, New LS, Neo AH, Goh CW, Browne ER, Chan EC. Chng HT, et al. Among authors: new ls. Brain Res. 2009 Jan 28;1251:80-6. doi: 10.1016/j.brainres.2008.11.025. Epub 2008 Nov 19. Brain Res. 2009. PMID: 19046949

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