Bone RN - Search Results

1

Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo.

Bone RN, Icyuz M, Zhang Y, Zhang Y, Cui W, Wang H, Peng JB, Matthews QL, Siegal GP, Wu H. Bone RN, et al. Islets. 2012 Nov-Dec;4(6):366-78. doi: 10.4161/isl.22721. Epub 2012 Nov 1. Islets. 2012. PMID: 23183538 Free PMC article.

2

Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.

Zhang Y, Zhang Y, Bone RN, Cui W, Peng JB, Siegal GP, Wang H, Wu H. Zhang Y, et al. Among authors: bone rn. PLoS One. 2012;7(5):e36675. doi: 10.1371/journal.pone.0036675. Epub 2012 May 7. PLoS One. 2012. PMID: 22586489 Free PMC article.

3

Genetic modulation of islet β-cell iPLA₂β expression provides evidence for its impact on β-cell apoptosis and autophagy.

Lei X, Bone RN, Ali T, Wohltmann M, Gai Y, Goodwin KJ, Bohrer AE, Turk J, Ramanadham S. Lei X, et al. Among authors: bone rn. Islets. 2013 Jan-Feb;5(1):29-44. doi: 10.4161/isl.23758. Epub 2013 Jan 1. Islets. 2013. PMID: 23411472 Free PMC article.

4

Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes.

Ali T, Kokotos G, Magrioti V, Bone RN, Mobley JA, Hancock W, Ramanadham S. Ali T, et al. Among authors: bone rn. PLoS One. 2013 Aug 20;8(8):e71748. doi: 10.1371/journal.pone.0071748. eCollection 2013. PLoS One. 2013. PMID: 23977134 Free PMC article.

5

Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.

Bone RN, Gai Y, Magrioti V, Kokotou MG, Ali T, Lei X, Tse HM, Kokotos G, Ramanadham S. Bone RN, et al. Diabetes. 2015 Feb;64(2):541-54. doi: 10.2337/db14-0097. Epub 2014 Sep 11. Diabetes. 2015. PMID: 25213337 Free PMC article.

6

Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.

Lei X, Bone RN, Ali T, Zhang S, Bohrer A, Tse HM, Bidasee KR, Ramanadham S. Lei X, et al. Among authors: bone rn. Endocrinology. 2014 Sep;155(9):3352-64. doi: 10.1210/en.2013-2134. Epub 2014 Jul 8. Endocrinology. 2014. PMID: 25004092 Free PMC article.

7

Lipid mediators and biomarkers associated with type 1 diabetes development.

Nelson AJ, Stephenson DJ, Bone RN, Cardona CL, Park MA, Tusing YG, Lei X, Kokotos G, Graves CL, Mathews CE, Kramer J, Hessner MJ, Chalfant CE, Ramanadham S. Nelson AJ, et al. Among authors: bone rn. JCI Insight. 2020 Aug 20;5(16):e138034. doi: 10.1172/jci.insight.138034. JCI Insight. 2020. PMID: 32814707 Free PMC article.

8

Changes in immunofluorescence staining during islet regeneration in a cystic fibrosis-related diabetes (CFRD) ferret model.

Mohammed SM, Bone RN, Aquino JDC, Mirmira RG, Evans-Molina C, Ismail HM. Mohammed SM, et al. Among authors: bone rn. Islets. 2024 Dec 31;16(1):2436696. doi: 10.1080/19382014.2024.2436696. Epub 2024 Dec 6. Islets. 2024. PMID: 39641365 Free PMC article.

9

Calcium-independent phospholipases A2 and their roles in biological processes and diseases.

Ramanadham S, Ali T, Ashley JW, Bone RN, Hancock WD, Lei X. Ramanadham S, et al. Among authors: bone rn. J Lipid Res. 2015 Sep;56(9):1643-68. doi: 10.1194/jlr.R058701. Epub 2015 May 28. J Lipid Res. 2015. PMID: 26023050 Free PMC article. Review.

10

Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2).

Ashley JW, Hancock WD, Nelson AJ, Bone RN, Tse HM, Wohltmann M, Turk J, Ramanadham S. Ashley JW, et al. Among authors: bone rn. J Biol Chem. 2016 Oct 28;291(44):23268-23281. doi: 10.1074/jbc.M116.754945. Epub 2016 Sep 20. J Biol Chem. 2016. PMID: 27650501 Free PMC article.

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