Rotili D - Search Results

1

Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.

Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, Fraga M, Esteller M, Altucci L, Mai A. Rotili D, et al. J Med Chem. 2012 Dec 27;55(24):10937-47. doi: 10.1021/jm3011614. Epub 2012 Dec 12. J Med Chem. 2012. PMID: 23189967

2

Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A.

Mai A, Massa S, Pezzi R, Rotili D, Loidl P, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2003 Nov 6;46(23):4826-9. doi: 10.1021/jm034167p. J Med Chem. 2003. PMID: 14584932

3

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Among authors: rotili d. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

4

Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

Mai A, Massa S, Pezzi R, Simeoni S, Rotili D, Nebbioso A, Scognamiglio A, Altucci L, Loidl P, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2005 May 5;48(9):3344-53. doi: 10.1021/jm049002a. J Med Chem. 2005. PMID: 15857140

5

A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast.

Ornaghi P, Rotili D, Sbardella G, Mai A, Filetici P. Ornaghi P, et al. Among authors: rotili d. Biochem Pharmacol. 2005 Sep 15;70(6):911-7. doi: 10.1016/j.bcp.2005.06.013. Biochem Pharmacol. 2005. PMID: 16043126

6

Exploring the connection unit in the HDAC inhibitor pharmacophore model: novel uracil-based hydroxamates.

Mai A, Massa S, Rotili D, Pezzi R, Bottoni P, Scatena R, Meraner J, Brosch G. Mai A, et al. Among authors: rotili d. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4656-61. doi: 10.1016/j.bmcl.2005.07.081. Bioorg Med Chem Lett. 2005. PMID: 16165353

7

6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase.

Bartolini S, Mai A, Artico M, Paesano N, Rotili D, Spadafora C, Sbardella G. Bartolini S, et al. Among authors: rotili d. J Med Chem. 2005 Nov 3;48(22):6776-8. doi: 10.1021/jm0507330. J Med Chem. 2005. PMID: 16250634

8

Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpak IA chiral stationary phase.

Cirilli R, Ferretti R, Gallinella B, La Torre F, Mai A, Rotili D. Cirilli R, et al. Among authors: rotili d. J Sep Sci. 2006 Jul;29(10):1399-406. doi: 10.1002/jssc.200600019. J Sep Sci. 2006. PMID: 16894784

9

6-alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): novel regulators of cell differentiation and proliferation.

Sbardella G, Bartolini S, Castellano S, Artico M, Paesano N, Rotili D, Spadafora C, Mai A. Sbardella G, et al. Among authors: rotili d. ChemMedChem. 2006 Oct;1(10):1073-80. doi: 10.1002/cmdc.200600139. ChemMedChem. 2006. PMID: 16944545

10

Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors.

Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2006 Oct 5;49(20):6046-56. doi: 10.1021/jm0605536. J Med Chem. 2006. PMID: 17004718

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