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582 results

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Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy.
Borgegård T, Gustavsson S, Nilsson C, Parpal S, Klintenberg R, Berg AL, Rosqvist S, Serneels L, Svensson S, Olsson F, Jin S, Yan H, Wanngren J, Jureus A, Ridderstad-Wollberg A, Wollberg P, Stockling K, Karlström H, Malmberg A, Lund J, Arvidsson PI, De Strooper B, Lendahl U, Lundkvist J. Borgegård T, et al. Among authors: svensson s. J Neurosci. 2012 Nov 28;32(48):17297-305. doi: 10.1523/JNEUROSCI.1451-12.2012. J Neurosci. 2012. PMID: 23197721 Free PMC article.
Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS.
Georgievska B, Gustavsson S, Lundkvist J, Neelissen J, Eketjäll S, Ramberg V, Bueters T, Agerman K, Juréus A, Svensson S, Berg S, Fälting J, Lendahl U. Georgievska B, et al. Among authors: svensson s. J Neurochem. 2015 Feb;132(4):477-86. doi: 10.1111/jnc.12937. Epub 2014 Sep 18. J Neurochem. 2015. PMID: 25156639 Free article.
AZD2184: a radioligand for sensitive detection of beta-amyloid deposits.
Johnson AE, Jeppsson F, Sandell J, Wensbo D, Neelissen JA, Juréus A, Ström P, Norman H, Farde L, Svensson SP. Johnson AE, et al. Among authors: svensson sp. J Neurochem. 2009 Mar;108(5):1177-86. doi: 10.1111/j.1471-4159.2008.05861.x. Epub 2009 Jan 24. J Neurochem. 2009. PMID: 19141073 Free article.
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
Forsberg A, Juréus A, Cselényi Z, Eriksdotter M, Freund-Levi Y, Jeppsson F, Swahn BM, Sandell J, Julin P, Schou M, Andersson J, Johnström P, Varnäs K, Halldin C, Farde L, Svensson S. Forsberg A, et al. Among authors: svensson s. Eur J Nucl Med Mol Imaging. 2013 Apr;40(4):580-93. doi: 10.1007/s00259-012-2322-6. Epub 2013 Jan 17. Eur J Nucl Med Mol Imaging. 2013. PMID: 23324871 Free PMC article.
Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for beta-amyloid plaques.
Swahn BM, Wensbo D, Sandell J, Sohn D, Slivo C, Pyring D, Malmström J, Arzel E, Vallin M, Bergh M, Jeppsson F, Johnson AE, Juréus A, Neelissen J, Svensson S. Swahn BM, et al. Among authors: svensson s. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1976-80. doi: 10.1016/j.bmcl.2010.01.105. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20153963
Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand.
Cselényi Z, Jönhagen ME, Forsberg A, Halldin C, Julin P, Schou M, Johnström P, Varnäs K, Svensson S, Farde L. Cselényi Z, et al. Among authors: svensson s. J Nucl Med. 2012 Mar;53(3):415-24. doi: 10.2967/jnumed.111.094029. Epub 2012 Feb 9. J Nucl Med. 2012. PMID: 22323782 Free article.
Radiosynthesis, In Vitro and In Vivo Evaluation of [18F]CBD-2115 as a First-in-Class Radiotracer for Imaging 4R-Tauopathies.
Lindberg A, Knight AC, Sohn D, Rakos L, Tong J, Radelet A, Mason NS, Stehouwer JS, Lopresti BJ, Klunk WE, Sandell J, Sandberg A, Hammarström P, Svensson S, Mathis CA, Vasdev N. Lindberg A, et al. Among authors: svensson s. ACS Chem Neurosci. 2021 Feb 17;12(4):596-602. doi: 10.1021/acschemneuro.0c00801. Epub 2021 Jan 26. ACS Chem Neurosci. 2021. PMID: 33497190 Free PMC article.
582 results