Klenerman D - Search Results

1

Ubiquitin chain conformation regulates recognition and activity of interacting proteins.

Ye Y, Blaser G, Horrocks MH, Ruedas-Rama MJ, Ibrahim S, Zhukov AA, Orte A, Klenerman D, Jackson SE, Komander D. Ye Y, et al. Among authors: klenerman d. Nature. 2012 Dec 13;492(7428):266-70. doi: 10.1038/nature11722. Epub 2012 Dec 2. Nature. 2012. PMID: 23201676 Free PMC article.

2

Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection.

Orte A, Clarke R, Balasubramanian S, Klenerman D. Orte A, et al. Among authors: klenerman d. Anal Chem. 2006 Nov 15;78(22):7707-15. doi: 10.1021/ac061122y. Anal Chem. 2006. PMID: 17105162

3

Optimized threshold selection for single-molecule two-color fluorescence coincidence spectroscopy.

Clarke RW, Orte A, Klenerman D. Clarke RW, et al. Among authors: klenerman d. Anal Chem. 2007 Apr 1;79(7):2771-7. doi: 10.1021/ac062188w. Epub 2007 Mar 8. Anal Chem. 2007. PMID: 17343363

4

Single-molecule analysis of human telomerase monomer.

Alves D, Li H, Codrington R, Orte A, Ren X, Klenerman D, Balasubramanian S. Alves D, et al. Among authors: klenerman d. Nat Chem Biol. 2008 May;4(5):287-9. doi: 10.1038/nchembio.82. Nat Chem Biol. 2008. PMID: 18391947

5

Evidence of an intermediate and parallel pathways in protein unfolding from single-molecule fluorescence.

Orte A, Craggs TD, White SS, Jackson SE, Klenerman D. Orte A, et al. Among authors: klenerman d. J Am Chem Soc. 2008 Jun 25;130(25):7898-907. doi: 10.1021/ja709973m. Epub 2008 May 29. J Am Chem Soc. 2008. PMID: 18507381

6

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence.

Orte A, Birkett NR, Clarke RW, Devlin GL, Dobson CM, Klenerman D. Orte A, et al. Among authors: klenerman d. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14424-9. doi: 10.1073/pnas.0803086105. Epub 2008 Sep 16. Proc Natl Acad Sci U S A. 2008. PMID: 18796612 Free PMC article.

7

Fluorescence coincidence spectroscopy for single-molecule fluorescence resonance energy-transfer measurements.

Orte A, Clarke RW, Klenerman D. Orte A, et al. Among authors: klenerman d. Anal Chem. 2008 Nov 15;80(22):8389-97. doi: 10.1021/ac8009092. Epub 2008 Oct 15. Anal Chem. 2008. PMID: 18855410

8

Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations.

Ashbridge B, Orte A, Yeoman JA, Kirwan M, Vulliamy T, Dokal I, Klenerman D, Balasubramanian S. Ashbridge B, et al. Among authors: klenerman d. Biochemistry. 2009 Nov 24;48(46):10858-65. doi: 10.1021/bi901373e. Biochemistry. 2009. PMID: 19835419 Free PMC article.

9

Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence.

Chiou A, Hägglöf P, Orte A, Chen AY, Dunne PD, Belorgey D, Karlsson-Li S, Lomas DA, Klenerman D. Chiou A, et al. Among authors: klenerman d. Biophys J. 2009 Oct 21;97(8):2306-15. doi: 10.1016/j.bpj.2009.07.057. Biophys J. 2009. PMID: 19843463 Free PMC article.

10

RNA conformation in catalytically active human telomerase.

Yeoman JA, Orte A, Ashbridge B, Klenerman D, Balasubramanian S. Yeoman JA, et al. Among authors: klenerman d. J Am Chem Soc. 2010 Mar 10;132(9):2852-3. doi: 10.1021/ja909383n. J Am Chem Soc. 2010. PMID: 20148555 Free PMC article.

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