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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: sack mn. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. Retraction in: Nature. 2014 Feb 27;506(7489):516. doi: 10.1038/nature12897 PMID: 23201684 Retracted.
Wnt signaling regulates hepatic metabolism.
Liu H, Fergusson MM, Wu JJ, Rovira II, Liu J, Gavrilova O, Lu T, Bao J, Han D, Sack MN, Finkel T. Liu H, et al. Among authors: sack mn. Sci Signal. 2011 Feb 1;4(158):ra6. doi: 10.1126/scisignal.2001249. Sci Signal. 2011. PMID: 21285411 Free PMC article.
The role of comorbidities in cardioprotection.
Sack MN, Murphy E. Sack MN, et al. J Cardiovasc Pharmacol Ther. 2011 Sep-Dec;16(3-4):267-72. doi: 10.1177/1074248411408313. J Cardiovasc Pharmacol Ther. 2011. PMID: 21821527 Free PMC article. Review.
Mitochondrial metabolism, sirtuins, and aging.
Sack MN, Finkel T. Sack MN, et al. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a013102. doi: 10.1101/cshperspect.a013102. Cold Spring Harb Perspect Biol. 2012. PMID: 23209156 Free PMC article. Review.
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy.
Webster BR, Scott I, Han K, Li JH, Lu Z, Stevens MV, Malide D, Chen Y, Samsel L, Connelly PS, Daniels MP, McCoy JP Jr, Combs CA, Gucek M, Sack MN. Webster BR, et al. Among authors: sack mn. J Cell Sci. 2013 Nov 1;126(Pt 21):4843-9. doi: 10.1242/jcs.131300. Epub 2013 Sep 4. J Cell Sci. 2013. PMID: 24006259 Free PMC article.
Cyclophilin D modulates mitochondrial acetylome.
Nguyen TT, Wong R, Menazza S, Sun J, Chen Y, Wang G, Gucek M, Steenbergen C, Sack MN, Murphy E. Nguyen TT, et al. Among authors: sack mn. Circ Res. 2013 Dec 6;113(12):1308-19. doi: 10.1161/CIRCRESAHA.113.301867. Epub 2013 Sep 23. Circ Res. 2013. PMID: 24062335 Free PMC article.
148 results