Sorci L - Search Results

1

Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.

Sorci L, Blaby IK, Rodionova IA, De Ingeniis J, Tkachenko S, de Crécy-Lagard V, Osterman AL. Sorci L, et al. J Bacteriol. 2013 Feb;195(4):726-32. doi: 10.1128/JB.02002-12. Epub 2012 Nov 30. J Bacteriol. 2013. PMID: 23204464 Free PMC article.

2

Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism.

Huang N, Sorci L, Zhang X, Brautigam CA, Li X, Raffaelli N, Magni G, Grishin NV, Osterman AL, Zhang H. Huang N, et al. Among authors: sorci l. Structure. 2008 Feb;16(2):196-209. doi: 10.1016/j.str.2007.11.017. Structure. 2008. PMID: 18275811 Free PMC article.

3

Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon.

Rodionov DA, Li X, Rodionova IA, Yang C, Sorci L, Dervyn E, Martynowski D, Zhang H, Gelfand MS, Osterman AL. Rodionov DA, et al. Among authors: sorci l. Nucleic Acids Res. 2008 Apr;36(6):2032-46. doi: 10.1093/nar/gkn046. Epub 2008 Feb 14. Nucleic Acids Res. 2008. PMID: 18276644 Free PMC article.

4

Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis.

Sorci L, Martynowski D, Rodionov DA, Eyobo Y, Zogaj X, Klose KE, Nikolaev EV, Magni G, Zhang H, Osterman AL. Sorci L, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3083-8. doi: 10.1073/pnas.0811718106. Epub 2009 Feb 9. Proc Natl Acad Sci U S A. 2009. PMID: 19204287 Free PMC article.

5

Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.

Sorci L, Pan Y, Eyobo Y, Rodionova I, Huang N, Kurnasov O, Zhong S, MacKerell AD Jr, Zhang H, Osterman AL. Sorci L, et al. Chem Biol. 2009 Aug 28;16(8):849-61. doi: 10.1016/j.chembiol.2009.07.006. Chem Biol. 2009. PMID: 19716475 Free PMC article.

6

Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement.

Huang N, Kolhatkar R, Eyobo Y, Sorci L, Rodionova I, Osterman AL, Mackerell AD, Zhang H. Huang N, et al. Among authors: sorci l. J Med Chem. 2010 Jul 22;53(14):5229-39. doi: 10.1021/jm100377f. J Med Chem. 2010. PMID: 20578699 Free PMC article.

7

Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection.

Sorci L, Blaby I, De Ingeniis J, Gerdes S, Raffaelli N, de Crécy Lagard V, Osterman A. Sorci L, et al. J Biol Chem. 2010 Dec 10;285(50):39490-9. doi: 10.1074/jbc.M110.185629. Epub 2010 Oct 6. J Biol Chem. 2010. PMID: 20926389 Free PMC article.

8

Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family.

Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N. Galeazzi L, et al. Among authors: sorci l. J Biol Chem. 2011 Nov 18;286(46):40365-75. doi: 10.1074/jbc.M111.275818. Epub 2011 Sep 27. J Biol Chem. 2011. PMID: 21953451 Free PMC article.

9

Glutamine versus ammonia utilization in the NAD synthetase family.

De Ingeniis J, Kazanov MD, Shatalin K, Gelfand MS, Osterman AL, Sorci L. De Ingeniis J, et al. Among authors: sorci l. PLoS One. 2012;7(6):e39115. doi: 10.1371/journal.pone.0039115. Epub 2012 Jun 15. PLoS One. 2012. PMID: 22720044 Free PMC article.

10

Genomics-guided analysis of NAD recycling yields functional elucidation of COG1058 as a new family of pyrophosphatases.

Cialabrini L, Ruggieri S, Kazanov MD, Sorci L, Mazzola F, Orsomando G, Osterman AL, Raffaelli N. Cialabrini L, et al. Among authors: sorci l. PLoS One. 2013 Jun 12;8(6):e65595. doi: 10.1371/journal.pone.0065595. Print 2013. PLoS One. 2013. PMID: 23776507 Free PMC article.

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