Radu M - Search Results

1

Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.

Kosoff R, Chow HY, Radu M, Chernoff J. Kosoff R, et al. Among authors: radu m. J Biol Chem. 2013 Jan 11;288(2):974-83. doi: 10.1074/jbc.M112.422295. Epub 2012 Nov 30. J Biol Chem. 2013. PMID: 23204526 Free PMC article.

2

ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling.

Radu M, Rawat SJ, Beeser A, Iliuk A, Tao WA, Chernoff J. Radu M, et al. J Biol Chem. 2013 Jul 19;288(29):21117-21125. doi: 10.1074/jbc.M113.459719. Epub 2013 Jun 11. J Biol Chem. 2013. PMID: 23760270 Free PMC article.

3

Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.

Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Phee H, et al. Among authors: radu m. Elife. 2014 May 13;3:e02270. doi: 10.7554/eLife.02270. Elife. 2014. PMID: 24843022 Free PMC article.

4

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.

Kosoff RE, Aslan JE, Kostyak JC, Dulaimi E, Chow HY, Prudnikova TY, Radu M, Kunapuli SP, McCarty OJ, Chernoff J. Kosoff RE, et al. Among authors: radu m. Blood. 2015 May 7;125(19):2995-3005. doi: 10.1182/blood-2014-10-604504. Epub 2015 Mar 30. Blood. 2015. PMID: 25824689 Free PMC article.

5

p21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 Pathway.

Radu M, Lyle K, Hoeflich KP, Villamar-Cruz O, Koeppen H, Chernoff J. Radu M, et al. Mol Cell Biol. 2015 Dec;35(23):3990-4005. doi: 10.1128/MCB.00630-15. Epub 2015 Sep 21. Mol Cell Biol. 2015. PMID: 26391956 Free PMC article.

6

p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix.

Reddy PN, Radu M, Xu K, Wood J, Harris CE, Chernoff J, Williams DA. Reddy PN, et al. Among authors: radu m. Blood. 2016 Apr 21;127(16):1967-75. doi: 10.1182/blood-2016-01-693572. Epub 2016 Mar 1. Blood. 2016. PMID: 26932803 Free PMC article.

7

Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro.

Joseph GA, Lu M, Radu M, Lee JK, Burden SJ, Chernoff J, Krauss RS. Joseph GA, et al. Among authors: radu m. Mol Cell Biol. 2017 Feb 1;37(4):e00222-16. doi: 10.1128/MCB.00222-16. Print 2017 Feb 15. Mol Cell Biol. 2017. PMID: 27920252 Free PMC article.

8

Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response.

Binder P, Wang S, Radu M, Zin M, Collins L, Khan S, Li Y, Sekeres K, Humphreys N, Swanton E, Reid A, Pu F, Oceandy D, Guan K, Hille SS, Frey N, Müller OJ, Cartwright EJ, Chernoff J, Wang X, Liu W. Binder P, et al. Among authors: radu m. Circ Res. 2019 Mar;124(5):696-711. doi: 10.1161/CIRCRESAHA.118.312829. Circ Res. 2019. PMID: 30620686 Free PMC article.

9

The DeMSTification of mammalian Ste20 kinases.

Radu M, Chernoff J. Radu M, et al. Curr Biol. 2009 May 26;19(10):R421-5. doi: 10.1016/j.cub.2009.04.022. Curr Biol. 2009. PMID: 19467213 Free article. Review.

10

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA. Dorrance AM, et al. Among authors: radu m. Blood. 2013 Mar 28;121(13):2474-82. doi: 10.1182/blood-2012-10-460709. Epub 2013 Jan 18. Blood. 2013. PMID: 23335370 Free PMC article.

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