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Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.
Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS, Jordan WH, Brown DD, Hoffman WP, Holtzman DM, Bales KR, Gitter BD, May PC, Paul SM, DeMattos RB. Racke MM, et al. Among authors: demattos rb. J Neurosci. 2005 Jan 19;25(3):629-36. doi: 10.1523/JNEUROSCI.4337-04.2005. J Neurosci. 2005. PMID: 15659599 Free PMC article.
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M. Wang Y, et al. Among authors: demattos rb. J Exp Med. 2016 May 2;213(5):667-75. doi: 10.1084/jem.20151948. Epub 2016 Apr 18. J Exp Med. 2016. PMID: 27091843 Free PMC article.
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB. Wang H, et al. Among authors: demattos rb. Mol Neurodegener. 2018 Dec 17;13(1):65. doi: 10.1186/s13024-018-0296-y. Mol Neurodegener. 2018. PMID: 30558641 Free PMC article.
β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage.
Portelius E, Dean RA, Andreasson U, Mattsson N, Westerlund A, Olsson M, Demattos RB, Racke MM, Zetterberg H, May PC, Blennow K. Portelius E, et al. Among authors: demattos rb. Alzheimers Res Ther. 2014 Nov 17;6(5-8):75. doi: 10.1186/s13195-014-0075-0. eCollection 2014. Alzheimers Res Ther. 2014. PMID: 25404952 Free PMC article.
Apolipoprotein E, amyloid, and Alzheimer disease.
Bales KR, Dodart JC, DeMattos RB, Holtzman DM, Paul SM. Bales KR, et al. Among authors: demattos rb. Mol Interv. 2002 Oct;2(6):363-75, 339. doi: 10.1124/mi.2.6.363. Mol Interv. 2002. PMID: 14993413 Review.
60 results