Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.
Pantophlet R, Wilson IA, Burton DR.
Pantophlet R, et al.
J Virol. 2003 May;77(10):5889-901. doi: 10.1128/jvi.77.10.5889-5901.2003.
J Virol. 2003.
PMID: 12719582
Free PMC article.
In a first study, we found that four alanine substitutions on the perimeter of the so-called Phe-43 cavity of gp120 could reduce binding of weakly neutralizing CD4-binding site antibodies (R. Pantophlet, E. O. Saphire, P. Poignard, P. W. H. I. Parren, I. A. Wilson, …
In a first study, we found that four alanine substitutions on the perimeter of the so-called Phe-43 cavity of gp120 could reduce binding of …