Dobbelstein M - Search Results

1

HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates.

Schulz R, Dobbelstein M, Moll UM. Schulz R, et al. Among authors: dobbelstein m. Oncoimmunology. 2012 Nov 1;1(8):1425-1426. doi: 10.4161/onci.21173. Oncoimmunology. 2012. PMID: 23243616 Free PMC article.

2

p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.

Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T, Ørntoft TF, Andersen CL, Dobbelstein M. Braun CJ, et al. Among authors: dobbelstein m. Cancer Res. 2008 Dec 15;68(24):10094-104. doi: 10.1158/0008-5472.CAN-08-1569. Cancer Res. 2008. PMID: 19074875 Free PMC article.

3

The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins.

Wolff S, Talos F, Palacios G, Beyer U, Dobbelstein M, Moll UM. Wolff S, et al. Among authors: dobbelstein m. Cell Death Differ. 2009 Aug;16(8):1108-17. doi: 10.1038/cdd.2009.25. Epub 2009 Mar 20. Cell Death Differ. 2009. PMID: 19300453 Free PMC article.

4

Brdm2 - an aberrant hypomorphic p63 allele.

Talos F, Wolff S, Beyer U, Dobbelstein M, Moll UM. Talos F, et al. Among authors: dobbelstein m. Cell Death Differ. 2010 Jan;17(1):184-186. doi: 10.1038/cdd.2009.158. Cell Death Differ. 2010. PMID: 20161489 Free PMC article. No abstract available.

5

p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis.

Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brück W, Moll UM. Talos F, et al. Among authors: dobbelstein m. Cell Death Differ. 2010 Dec;17(12):1816-29. doi: 10.1038/cdd.2010.131. Cell Death Differ. 2010. PMID: 21076477 Free PMC article.

6

While p73 is essential, p63 is completely dispensable for the development of the central nervous system.

Holembowski L, Schulz R, Talos F, Scheel A, Wolff S, Dobbelstein M, Moll U. Holembowski L, et al. Among authors: dobbelstein m. Cell Cycle. 2011 Feb 15;10(4):680-9. doi: 10.4161/cc.10.4.14859. Epub 2011 Feb 15. Cell Cycle. 2011. PMID: 21293190 Free PMC article.

7

Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes.

Beyer U, Moll-Rocek J, Moll UM, Dobbelstein M. Beyer U, et al. Among authors: dobbelstein m. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3624-9. doi: 10.1073/pnas.1016201108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300884 Free PMC article.

8

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.

Schulz R, Marchenko ND, Holembowski L, Fingerle-Rowson G, Pesic M, Zender L, Dobbelstein M, Moll UM. Schulz R, et al. Among authors: dobbelstein m. J Exp Med. 2012 Feb 13;209(2):275-89. doi: 10.1084/jem.20111117. Epub 2012 Jan 23. J Exp Med. 2012. PMID: 22271573 Free PMC article.

9

HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.

Schulz R, Streller F, Scheel AH, Rüschoff J, Reinert MC, Dobbelstein M, Marchenko ND, Moll UM. Schulz R, et al. Among authors: dobbelstein m. Cell Death Dis. 2014 Jan 2;5(1):e980. doi: 10.1038/cddis.2013.508. Cell Death Dis. 2014. PMID: 24384723 Free PMC article.

10

Targeting tumour-supportive cellular machineries in anticancer drug development.

Dobbelstein M, Moll U. Dobbelstein M, et al. Nat Rev Drug Discov. 2014 Mar;13(3):179-96. doi: 10.1038/nrd4201. Nat Rev Drug Discov. 2014. PMID: 24577400 Review.

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