Wang J - Search Results

1

MMP inhibition by barbiturate homodimers.

Wang J, Radomski MW, Medina C, Gilmer JF. Wang J, et al. Bioorg Med Chem Lett. 2013 Jan 15;23(2):444-7. doi: 10.1016/j.bmcl.2012.11.063. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23246356

2

Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).

Sharma R, Majer F, Peta VK, Wang J, Keaveney R, Kelleher D, Long A, Gilmer JF. Sharma R, et al. Among authors: wang j. Bioorg Med Chem. 2010 Sep 15;18(18):6886-95. doi: 10.1016/j.bmc.2010.07.030. Epub 2010 Jul 19. Bioorg Med Chem. 2010. PMID: 20713311

3

N-substituted homopiperazine barbiturates as gelatinase inhibitors.

Wang J, Medina C, Radomski MW, Gilmer JF. Wang J, et al. Bioorg Med Chem. 2011 Aug 15;19(16):4985-99. doi: 10.1016/j.bmc.2011.06.055. Epub 2011 Jun 25. Bioorg Med Chem. 2011. PMID: 21764590

4

Design of barbiturate-nitrate hybrids that inhibit MMP-9 activity and secretion.

Wang J, O'Sullivan S, Harmon S, Keaveny R, Radomski MW, Medina C, Gilmer JF. Wang J, et al. J Med Chem. 2012 Mar 8;55(5):2154-62. doi: 10.1021/jm201352k. Epub 2012 Feb 23. J Med Chem. 2012. PMID: 22248361

5

New fluorescent bile acids: synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid.

Májer F, Salomon JJ, Sharma R, Etzbach SV, Najib MN, Keaveny R, Long A, Wang J, Ehrhardt C, Gilmer JF. Májer F, et al. Among authors: wang j. Bioorg Med Chem. 2012 Mar 1;20(5):1767-78. doi: 10.1016/j.bmc.2012.01.002. Epub 2012 Jan 12. Bioorg Med Chem. 2012. PMID: 22316556

6

New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.

Májer F, Sharma R, Mullins C, Keogh L, Phipps S, Duggan S, Kelleher D, Keely S, Long A, Radics G, Wang J, Gilmer JF. Májer F, et al. Among authors: wang j. Bioorg Med Chem. 2014 Jan 1;22(1):256-68. doi: 10.1016/j.bmc.2013.11.029. Epub 2013 Nov 23. Bioorg Med Chem. 2014. PMID: 24332653

7

Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer's Disease.

Jones M, Wang J, Harmon S, Kling B, Heilmann J, Gilmer JF. Jones M, et al. Among authors: wang j. Molecules. 2016 Apr 1;21(4):440. doi: 10.3390/molecules21040440. Molecules. 2016. PMID: 27534722 Free PMC article.

8

Inhibition of matrix metalloproteinase-9 by a barbiturate-nitrate hybrid ameliorates dextran sulphate sodium-induced colitis: effect on inflammation-related genes.

O'Sullivan S, Wang J, Pigott MT, Docherty N, Boyle N, Lis SK, Gilmer JF, Medina C. O'Sullivan S, et al. Among authors: wang j. Br J Pharmacol. 2017 Apr;174(7):512-524. doi: 10.1111/bph.13712. Epub 2017 Feb 24. Br J Pharmacol. 2017. PMID: 28079248 Free PMC article.

9

Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults.

Wang J, Radics G, Whelehan M, OʼDriscoll A, Healy AM, Gilmer JF, Ledwidge M. Wang J, et al. Acta Haematol. 2017;138(4):223-232. doi: 10.1159/000480632. Epub 2018 Jan 5. Acta Haematol. 2017. PMID: 29301124 Clinical Trial.

10

Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway.

O'Sullivan S, Wang J, Radomski MW, Gilmer JF, Medina C. O'Sullivan S, et al. Among authors: wang j. Biomolecules. 2020 May 25;10(5):808. doi: 10.3390/biom10050808. Biomolecules. 2020. PMID: 32466182 Free PMC article.

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