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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
Piao L, Sidhu VK, Fang YH, Ryan JJ, Parikh KS, Hong Z, Toth PT, Morrow E, Kutty S, Lopaschuk GD, Archer SL. Piao L, et al. Among authors: kutty s. J Mol Med (Berl). 2013 Mar;91(3):333-46. doi: 10.1007/s00109-012-0982-0. Epub 2012 Dec 18. J Mol Med (Berl). 2013. PMID: 23247844 Free PMC article.
Right ventricular adaptation and failure in pulmonary arterial hypertension.
Ryan JJ, Huston J, Kutty S, Hatton ND, Bowman L, Tian L, Herr JE, Johri AM, Archer SL. Ryan JJ, et al. Among authors: kutty s. Can J Cardiol. 2015 Apr;31(4):391-406. doi: 10.1016/j.cjca.2015.01.023. Epub 2015 Jan 29. Can J Cardiol. 2015. PMID: 25840092 Free PMC article. Review.
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, Kutty S, Provencher S, Bonnet S, Sutendra G, Archer SL. Tian L, et al. Among authors: kutty s. Circ Res. 2020 Jun 5;126(12):1723-1745. doi: 10.1161/CIRCRESAHA.120.316443. Epub 2020 Mar 27. Circ Res. 2020. PMID: 32216531 Free PMC article.
Persistence of right ventricular dysfunction and altered morphometry in asymptomatic preterm Infants through one year of age: Cardiac phenotype of prematurity.
Erickson CT, Patel MD, Choudhry S, Bisselou KS, Sekarski T, Craft M, Li L, Khuffash AE, Hamvas A, Kutty S, Singh GK, Levy PT. Erickson CT, et al. Among authors: kutty s. Cardiol Young. 2019 Jul;29(7):945-953. doi: 10.1017/S1047951119001161. Epub 2019 Jul 9. Cardiol Young. 2019. PMID: 31287038 Free PMC article.
490 results