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The B subunit of an AB5 toxin produced by Salmonella enterica serovar Typhi up-regulates chemokines, cytokines, and adhesion molecules in human macrophage, colonic epithelial, and brain microvascular endothelial cell lines.
Wang H, Paton JC, Herdman BP, Rogers TJ, Beddoe T, Paton AW. Wang H, et al. Among authors: herdman bp. Infect Immun. 2013 Mar;81(3):673-83. doi: 10.1128/IAI.01043-12. Epub 2012 Dec 17. Infect Immun. 2013. PMID: 23250951 Free PMC article.
Structural basis of subtilase cytotoxin SubAB assembly.
Le Nours J, Paton AW, Byres E, Troy S, Herdman BP, Johnson MD, Paton JC, Rossjohn J, Beddoe T. Le Nours J, et al. Among authors: herdman bp. J Biol Chem. 2013 Sep 20;288(38):27505-27516. doi: 10.1074/jbc.M113.462622. Epub 2013 Aug 6. J Biol Chem. 2013. PMID: 23921389 Free PMC article.
Structure aided design of a Neu5Gc specific lectin.
Day CJ, Paton AW, Higgins MA, Shewell LK, Jen FE, Schulz BL, Herdman BP, Paton JC, Jennings MP. Day CJ, et al. Among authors: herdman bp. Sci Rep. 2017 May 4;7(1):1495. doi: 10.1038/s41598-017-01522-9. Sci Rep. 2017. PMID: 28473713 Free PMC article.