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Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
Wurfel MM, Gordon AC, Holden TD, Radella F, Strout J, Kajikawa O, Ruzinski JT, Rona G, Black RA, Stratton S, Jarvik GP, Hajjar AM, Nickerson DA, Rieder M, Sevransky J, Maloney JP, Moss M, Martin G, Shanholtz C, Garcia JG, Gao L, Brower R, Barnes KC, Walley KR, Russell JA, Martin TR. Wurfel MM, et al. Am J Respir Crit Care Med. 2008 Oct 1;178(7):710-20. doi: 10.1164/rccm.200803-462OC. Epub 2008 Jul 17. Am J Respir Crit Care Med. 2008. PMID: 18635889 Free PMC article.
Genetic variation in the FAS gene and associations with acute lung injury.
Glavan BJ, Holden TD, Goss CH, Black RA, Neff MJ, Nathens AB, Martin TR, Wurfel MM; ARDSnet Investigators. Glavan BJ, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2011 Feb 1;183(3):356-63. doi: 10.1164/rccm.201003-0351OC. Epub 2010 Sep 2. Am J Respir Crit Care Med. 2011. PMID: 20813889 Free PMC article.
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.
Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD. Meyer NJ, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. doi: 10.1164/rccm.201005-0701OC. Epub 2011 Jan 21. Am J Respir Crit Care Med. 2011. PMID: 21257790 Free PMC article.
Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.
Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H; Trauma ALI SNP Consortium (TASC) investigators. Christie JD, et al. Among authors: wurfel mm. PLoS One. 2012;7(1):e28268. doi: 10.1371/journal.pone.0028268. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295056 Free PMC article.
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC; National Heart, Lung, and Blood Institute (NHLBI) GO Exome Sequencing Project; Lung GO; Gibson RL, Bamshad MJ. Emond MJ, et al. Nat Genet. 2012 Jul 8;44(8):886-9. doi: 10.1038/ng.2344. Nat Genet. 2012. PMID: 22772370 Free PMC article.
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI. Ko DC, et al. Among authors: wurfel mm. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2343-52. doi: 10.1073/pnas.1206701109. Epub 2012 Jul 25. Proc Natl Acad Sci U S A. 2012. PMID: 22837397 Free PMC article.
167 results