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The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro.
Warner N, Locarnini S, Kuiper M, Bartholomeusz A, Ayres A, Yuen L, Shaw T. Warner N, et al. Among authors: kuiper m. Antimicrob Agents Chemother. 2007 Jul;51(7):2285-92. doi: 10.1128/AAC.01499-06. Epub 2007 Apr 16. Antimicrob Agents Chemother. 2007. PMID: 17438047 Free PMC article.
Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus.
Monk IR, Shaikh N, Begg SL, Gajdiss M, Sharkey LKR, Lee JYH, Pidot SJ, Seemann T, Kuiper M, Winnen B, Hvorup R, Collins BM, Bierbaum G, Udagedara SR, Morey JR, Pulyani N, Howden BP, Maher MJ, McDevitt CA, King GF, Stinear TP. Monk IR, et al. Among authors: kuiper m. Nat Commun. 2019 Jul 11;10(1):3067. doi: 10.1038/s41467-019-10932-4. Nat Commun. 2019. PMID: 31296851 Free PMC article.
456 results