Deb S - Search Results

1

Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl.

Vaughan CA, Singh S, Windle B, Yeudall WA, Frum R, Grossman SR, Deb SP, Deb S. Vaughan CA, et al. Among authors: deb s, deb sp. Genes Cancer. 2012 Jul;3(7-8):491-502. doi: 10.1177/1947601912462719. Genes Cancer. 2012. PMID: 23264849 Free PMC article.

2

p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity.

Vaughan CA, Singh S, Windle B, Sankala HM, Graves PR, Andrew Yeudall W, Deb SP, Deb S. Vaughan CA, et al. Among authors: deb s, deb sp. Arch Biochem Biophys. 2012 Feb 1;518(1):79-88. doi: 10.1016/j.abb.2011.12.006. Epub 2011 Dec 16. Arch Biochem Biophys. 2012. PMID: 22198284 Free PMC article.

3

Allele specific gain-of-function activity of p53 mutants in lung cancer cells.

Vaughan CA, Frum R, Pearsall I, Singh S, Windle B, Yeudall A, Deb SP, Deb S. Vaughan CA, et al. Among authors: deb s, deb sp. Biochem Biophys Res Commun. 2012 Nov 9;428(1):6-10. doi: 10.1016/j.bbrc.2012.09.029. Epub 2012 Sep 16. Biochem Biophys Res Commun. 2012. PMID: 22989750 Free PMC article.

4

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites.

Vaughan CA, Deb SP, Deb S, Windle B. Vaughan CA, et al. Among authors: deb s, deb sp. Oncotarget. 2014 Jan 30;5(2):417-27. doi: 10.18632/oncotarget.1708. Oncotarget. 2014. PMID: 24481480 Free PMC article.

5

Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter.

Vaughan CA, Pearsall I, Singh S, Windle B, Deb SP, Grossman SR, Yeudall WA, Deb S. Vaughan CA, et al. Among authors: deb s, deb sp. Oncotarget. 2016 Mar 15;7(11):12426-46. doi: 10.18632/oncotarget.6998. Oncotarget. 2016. PMID: 26820293 Free PMC article.

6

Human Oncoprotein MDM2 Up-regulates Expression of NF-κB2 Precursor p100 Conferring a Survival Advantage to Lung Cells.

Vaughan C, Mohanraj L, Singh S, Dumur CI, Ramamoorthy M, Garrett CT, Windle B, Yeudall WA, Deb S, Deb SP. Vaughan C, et al. Among authors: deb s, deb sp. Genes Cancer. 2011 Oct;2(10):943-55. doi: 10.1177/1947601911436008. Genes Cancer. 2011. PMID: 22701761 Free PMC article.

7

Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.

Vaughan CA, Singh S, Grossman SR, Windle B, Deb SP, Deb S. Vaughan CA, et al. Among authors: deb s, deb sp. Mol Oncol. 2017 Jun;11(6):696-711. doi: 10.1002/1878-0261.12068. Epub 2017 May 8. Mol Oncol. 2017. PMID: 28423230 Free PMC article.

8

Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells.

Singh S, Ramamoorthy M, Vaughan C, Yeudall WA, Deb S, Palit Deb S. Singh S, et al. Among authors: deb s. Cell Death Differ. 2013 Apr;20(4):558-66. doi: 10.1038/cdd.2012.153. Epub 2012 Dec 14. Cell Death Differ. 2013. PMID: 23238568 Free PMC article.

9

The growth arrest function of the human oncoprotein mouse double minute-2 is disabled by downstream mutation in cancer cells.

Zhou R, Frum R, Deb S, Deb SP. Zhou R, et al. Among authors: deb s, deb sp. Cancer Res. 2005 Mar 1;65(5):1839-48. doi: 10.1158/0008-5472.CAN-03-3755. Cancer Res. 2005. PMID: 15753382

10

MDM2 controls the timely expression of cyclin A to regulate the cell cycle.

Frum R, Ramamoorthy M, Mohanraj L, Deb S, Deb SP. Frum R, et al. Among authors: deb s, deb sp. Mol Cancer Res. 2009 Aug;7(8):1253-67. doi: 10.1158/1541-7786.MCR-08-0334. Epub 2009 Aug 11. Mol Cancer Res. 2009. PMID: 19671680 Free article.

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