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Page 1
Lead optimization of isocytosine-derived xanthine oxidase inhibitors.
Bajaj K, Burudkar S, Shah P, Keche A, Ghosh U, Tannu P, Khanna S, Srivastava A, Deshmukh NJ, Dixit A, Ahire Y, Damre A, Nemmani KV, Kulkarni-Almeida A, B-Rao C, Sharma R, Sivaramakrishnan H. Bajaj K, et al. Among authors: b rao c. Bioorg Med Chem Lett. 2013 Feb 1;23(3):834-8. doi: 10.1016/j.bmcl.2012.11.057. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23265878
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Khanna S, Burudkar S, Bajaj K, Shah P, Keche A, Ghosh U, Desai A, Srivastava A, Kulkarni-Almeida A, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Nemmani KV, Tannu P, Damre A, B-Rao C, Sharma R, Sivaramakrishnan H. Khanna S, et al. Among authors: b rao c. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7543-6. doi: 10.1016/j.bmcl.2012.10.029. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23122864
Cyclopentyl-pyrimidine based analogues as novel and potent IGF-1R inhibitor.
Aware V, Gaikwad N, Chavan S, Manohar S, Bose J, Khanna S, B-Rao C, Dixit N, Singh KS, Damre A, Sharma R, Patil S, Roychowdhury A. Aware V, et al. Among authors: b rao c. Eur J Med Chem. 2015 Mar 6;92:246-56. doi: 10.1016/j.ejmech.2014.12.053. Epub 2014 Dec 31. Eur J Med Chem. 2015. PMID: 25559205
A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis.
Dagia NM, Kamath DV, Bhatt P, Gupte RD, Dadarkar SS, Fonseca L, Agarwal G, Chetrapal-Kunwar A, Balachandran S, Srinivasan S, Bose J, Pari K, B-Rao C, Parkale SS, Gadekar PK, Rodge AH, Mandrekar N, Vishwakarma RA, Sharma S. Dagia NM, et al. Among authors: b rao c. Eur J Pharmacol. 2009 Apr 1;607(1-3):201-12. doi: 10.1016/j.ejphar.2009.02.031. Epub 2009 Feb 21. Eur J Pharmacol. 2009. PMID: 19239912
24 results