Gammage PA - Search Results

1

Alternative translation initiation augments the human mitochondrial proteome.

Kazak L, Reyes A, Duncan AL, Rorbach J, Wood SR, Brea-Calvo G, Gammage PA, Robinson AJ, Minczuk M, Holt IJ. Kazak L, et al. Among authors: gammage pa. Nucleic Acids Res. 2013 Feb 1;41(4):2354-69. doi: 10.1093/nar/gks1347. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275553 Free PMC article.

2

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome.

Rorbach J, Gammage PA, Minczuk M. Rorbach J, et al. Among authors: gammage pa. Nucleic Acids Res. 2012 May;40(9):4097-109. doi: 10.1093/nar/gkr1282. Epub 2012 Jan 11. Nucleic Acids Res. 2012. PMID: 22238376 Free PMC article.

3

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome.

Rorbach J, Gammage PA, Minczuk M. Rorbach J, et al. Among authors: gammage pa. Nucleic Acids Res. 2016 Jan 29;44(2):992. doi: 10.1093/nar/gkv1125. Epub 2015 Oct 19. Nucleic Acids Res. 2016. PMID: 26487634 Free PMC article. No abstract available.

4

Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs.

Gammage PA, Gaude E, Van Haute L, Rebelo-Guiomar P, Jackson CB, Rorbach J, Pekalski ML, Robinson AJ, Charpentier M, Concordet JP, Frezza C, Minczuk M. Gammage PA, et al. Nucleic Acids Res. 2016 Sep 19;44(16):7804-16. doi: 10.1093/nar/gkw676. Epub 2016 Jul 27. Nucleic Acids Res. 2016. PMID: 27466392 Free PMC article.

5

Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.

Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M. Gammage PA, et al. EMBO Mol Med. 2014 Apr;6(4):458-66. doi: 10.1002/emmm.201303672. Epub 2014 Feb 24. EMBO Mol Med. 2014. PMID: 24567072 Free PMC article.

6

MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome.

Rorbach J, Boesch P, Gammage PA, Nicholls TJ, Pearce SF, Patel D, Hauser A, Perocchi F, Minczuk M. Rorbach J, et al. Among authors: gammage pa. Mol Biol Cell. 2014 Sep 1;25(17):2542-55. doi: 10.1091/mbc.E14-01-0014. Epub 2014 Jul 9. Mol Biol Cell. 2014. PMID: 25009282 Free PMC article.

7

Engineered mtZFNs for Manipulation of Human Mitochondrial DNA Heteroplasmy.

Gammage PA, Van Haute L, Minczuk M. Gammage PA, et al. Methods Mol Biol. 2016;1351:145-62. doi: 10.1007/978-1-4939-3040-1_11. Methods Mol Biol. 2016. PMID: 26530680

8

Mitochondrial Genome Engineering: The Revolution May Not Be CRISPR-Ized.

Gammage PA, Moraes CT, Minczuk M. Gammage PA, et al. Trends Genet. 2018 Feb;34(2):101-110. doi: 10.1016/j.tig.2017.11.001. Epub 2017 Nov 24. Trends Genet. 2018. PMID: 29179920 Free PMC article. Review.

9

Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology.

Gammage PA, Minczuk M. Gammage PA, et al. Methods Mol Biol. 2018;1867:43-56. doi: 10.1007/978-1-4939-8799-3_4. Methods Mol Biol. 2018. PMID: 30155814

10

Therapeutic Manipulation of mtDNA Heteroplasmy: A Shifting Perspective.

Jackson CB, Turnbull DM, Minczuk M, Gammage PA. Jackson CB, et al. Among authors: gammage pa. Trends Mol Med. 2020 Jul;26(7):698-709. doi: 10.1016/j.molmed.2020.02.006. Epub 2020 Mar 26. Trends Mol Med. 2020. PMID: 32589937 Free article. Review.

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