Pasternak SH - Search Results

1

A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin-D detection.

Ta R, Suchy M, Tam JH, Li AX, Martinez-Santiesteban FS, Scholl TJ, Hudson RH, Bartha R, Pasternak SH. Ta R, et al. Among authors: pasternak sh. Contrast Media Mol Imaging. 2013 Mar-Apr;8(2):127-39. doi: 10.1002/cmmi.1502. Contrast Media Mol Imaging. 2013. PMID: 23281285 Free article.

2

Four-pool modeling of proton exchange processes in biological systems in the presence of MRI-paramagnetic chemical exchange saturation transfer (PARACEST) agents.

Li AX, Hudson RH, Barrett JW, Jones CK, Pasternak SH, Bartha R. Li AX, et al. Among authors: pasternak sh. Magn Reson Med. 2008 Nov;60(5):1197-206. doi: 10.1002/mrm.21752. Magn Reson Med. 2008. PMID: 18958857 Free article.

3

A paramagnetic chemical exchange-based MRI probe metabolized by cathepsin D: design, synthesis and cellular uptake studies.

Suchý M, Ta R, Li AX, Wojciechowski F, Pasternak SH, Bartha R, Hudson RH. Suchý M, et al. Among authors: pasternak sh. Org Biomol Chem. 2010 Jun 7;8(11):2560-6. doi: 10.1039/b926639a. Epub 2010 Mar 26. Org Biomol Chem. 2010. PMID: 20485791

4

Amyloid and Alzheimer's disease: inside and out.

Tam JH, Pasternak SH. Tam JH, et al. Among authors: pasternak sh. Can J Neurol Sci. 2012 May;39(3):286-98. doi: 10.1017/s0317167100013408. Can J Neurol Sci. 2012. PMID: 22547507 Review.

5

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.

Tam JH, Seah C, Pasternak SH. Tam JH, et al. Among authors: pasternak sh. Mol Brain. 2014 Aug 1;7:54. doi: 10.1186/s13041-014-0054-1. Mol Brain. 2014. PMID: 25085554 Free PMC article.

6

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes.

Tang W, Tam JH, Seah C, Chiu J, Tyrer A, Cregan SP, Meakin SO, Pasternak SH. Tang W, et al. Among authors: pasternak sh. Mol Brain. 2015 Jul 14;8:41. doi: 10.1186/s13041-015-0129-7. Mol Brain. 2015. PMID: 26170135 Free PMC article.

7

Prolonged In Vivo Retention of a Cathepsin D Targeted Optical Contrast Agent in a Mouse Model of Alzheimer's Disease.

Snir JA, Suchy M, Lawrence KS, Hudson RH, Pasternak SH, Bartha R. Snir JA, et al. Among authors: pasternak sh. J Alzheimers Dis. 2015;48(1):73-87. doi: 10.3233/JAD-150123. J Alzheimers Dis. 2015. PMID: 26401930

8

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP.

Tam JH, Pasternak SH. Tam JH, et al. Among authors: pasternak sh. J Vis Exp. 2015 Oct 17;(105):e53153. doi: 10.3791/53153. J Vis Exp. 2015. PMID: 26555118 Free PMC article.

9

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures.

Caetano FA, Dirk BS, Tam JH, Cavanagh PC, Goiko M, Ferguson SS, Pasternak SH, Dikeakos JD, de Bruyn JR, Heit B. Caetano FA, et al. Among authors: pasternak sh. PLoS Comput Biol. 2015 Dec 11;11(12):e1004634. doi: 10.1371/journal.pcbi.1004634. eCollection 2015 Dec. PLoS Comput Biol. 2015. PMID: 26657340 Free PMC article.

10

Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway.

Tam JH, Cobb MR, Seah C, Pasternak SH. Tam JH, et al. Among authors: pasternak sh. PLoS One. 2016 Oct 24;11(10):e0161445. doi: 10.1371/journal.pone.0161445. eCollection 2016. PLoS One. 2016. PMID: 27776132 Free PMC article.

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