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470 results

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A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers.
Libri V, Brown AP, Gambarota G, Haddad J, Shields GS, Dawes H, Pinato DJ, Hoffman E, Elliot PJ, Vlasuk GP, Jacobson E, Wilkins MR, Matthews PM. Libri V, et al. Among authors: matthews pm. PLoS One. 2012;7(12):e51395. doi: 10.1371/journal.pone.0051395. Epub 2012 Dec 20. PLoS One. 2012. PMID: 23284689 Free PMC article. Clinical Trial.
A multi-center randomized proof-of-concept clinical trial applying [¹⁸F]FDG-PET for evaluation of metabolic therapy with rosiglitazone XR in mild to moderate Alzheimer's disease.
Tzimopoulou S, Cunningham VJ, Nichols TE, Searle G, Bird NP, Mistry P, Dixon IJ, Hallett WA, Whitcher B, Brown AP, Zvartau-Hind M, Lotay N, Lai RY, Castiglia M, Jeter B, Matthews JC, Chen K, Bandy D, Reiman EM, Gold M, Rabiner EA, Matthews PM. Tzimopoulou S, et al. Among authors: matthews pm, matthews jc. J Alzheimers Dis. 2010;22(4):1241-56. doi: 10.3233/JAD-2010-100939. J Alzheimers Dis. 2010. PMID: 20930300 Clinical Trial.
Pragmatic study of orlistat 60 mg on abdominal obesity.
Thomas EL, Makwana A, Newbould R, Rao AW, Gambarota G, Frost G, Delafont B, Mishra RG, Matthews PM, Berk ES, Schwartz SM, Bell JD, Beaver JD. Thomas EL, et al. Among authors: matthews pm. Eur J Clin Nutr. 2011 Nov;65(11):1256-62. doi: 10.1038/ejcn.2011.108. Epub 2011 Jun 22. Eur J Clin Nutr. 2011. PMID: 21697820 Clinical Trial.
T2* measurement of the knee articular cartilage in osteoarthritis at 3T.
Newbould RD, Miller SR, Toms LD, Swann P, Tielbeek JA, Gold GE, Strachan RK, Taylor PC, Matthews PM, Brown AP. Newbould RD, et al. Among authors: matthews pm. J Magn Reson Imaging. 2012 Jun;35(6):1422-9. doi: 10.1002/jmri.23598. Epub 2012 Feb 7. J Magn Reson Imaging. 2012. PMID: 22314961 Free PMC article.
Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.
Owen DR, Guo Q, Kalk NJ, Colasanti A, Kalogiannopoulou D, Dimber R, Lewis YL, Libri V, Barletta J, Ramada-Magalhaes J, Kamalakaran A, Nutt DJ, Passchier J, Matthews PM, Gunn RN, Rabiner EA. Owen DR, et al. Among authors: matthews pm. J Cereb Blood Flow Metab. 2014 Jun;34(6):989-94. doi: 10.1038/jcbfm.2014.46. Epub 2014 Mar 19. J Cereb Blood Flow Metab. 2014. PMID: 24643083 Free PMC article. Clinical Trial.
TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.
Owen DR, Fan J, Campioli E, Venugopal S, Midzak A, Daly E, Harlay A, Issop L, Libri V, Kalogiannopoulou D, Oliver E, Gallego-Colon E, Colasanti A, Huson L, Rabiner EA, Suppiah P, Essagian C, Matthews PM, Papadopoulos V. Owen DR, et al. Among authors: matthews pm. Biochem J. 2017 Nov 21;474(23):3985-3999. doi: 10.1042/BCJ20170648. Biochem J. 2017. PMID: 29074640 Free PMC article. Clinical Trial.
470 results