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A MIF-Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2.
Krammer C, Kontos C, Dewor M, Hille K, Dalla Volta B, El Bounkari O, Taş K, Sinitski D, Brandhofer M, Megens RTA, Weber C, Schultz JR, Bernhagen J, Kapurniotu A. Krammer C, et al. Among authors: schultz jr. Chembiochem. 2021 Mar 16;22(6):1012-1019. doi: 10.1002/cbic.202000574. Epub 2020 Nov 30. Chembiochem. 2021. PMID: 33125165 Free PMC article.
Non-mitogenic FGF19 mRNA-based therapy for the treatment of experimental metabolic dysfunction-associated steatotic liver disease (MASLD).
Lopez-Pascual A, Russo-Cabrera JS, Ardaiz N, Palmer T, Graham AR, Uriarte I, Gomar C, Ruiz-Guillamon D, Latasa MU, Arechederra M, Fontanellas A, Monte MJ, Marin JJG, Berasain C, Del Rio CL, Fernandez-Barrena MG, Martini PGV, Schultz JR, Berraondo P, Avila MA. Lopez-Pascual A, et al. Among authors: schultz jr. Clin Sci (Lond). 2024 Oct 16;138(20):1265-1284. doi: 10.1042/CS20241137. Clin Sci (Lond). 2024. PMID: 39301694
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells.
Cao J, Markel A, Hanahoe E, Ketova T, Mihai C, Zalinger Z, Marquardt D, Amato NJ, Cheng YM, Reid DW, Dousis A, Giangrande PH, Schultz JR, Martini PGV, Finn PF. Cao J, et al. Among authors: schultz jr. Amino Acids. 2023 May;55(5):695-708. doi: 10.1007/s00726-023-03263-8. Epub 2023 Mar 21. Amino Acids. 2023. PMID: 36944899 Free PMC article.
Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria.
Schultz JR, Costa SK, Jachak GR, Hegde P, Zimmerman M, Pan Y, Josten M, Ejeh C, Hammerstad T, Sahl HG, Pereira PM, Pinho MG, Dartois V, Cheung A, Aldrich CC. Schultz JR, et al. J Med Chem. 2022 Oct 27;65(20):13910-13934. doi: 10.1021/acs.jmedchem.2c01151. Epub 2022 Oct 11. J Med Chem. 2022. PMID: 36219779 Free PMC article.
146 results