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Conserved host-pathogen PPIs. Globally conserved inter-species bacterial PPIs based conserved host-pathogen interactome derived novel target in C. pseudotuberculosis, C. diphtheriae, M. tuberculosis, C. ulcerans, Y. pestis, and E. coli targeted by Piper betel compounds.
Barh D, Gupta K, Jain N, Khatri G, León-Sicairos N, Canizalez-Roman A, Tiwari S, Verma A, Rahangdale S, Shah Hassan S, dos Santos AR, Ali A, Guimarães LC, Thiago Jucá Ramos R, Devarapalli P, Barve N, Bakhtiar M, Kumavath R, Ghosh P, Miyoshi A, Silva A, Kumar A, Misra AN, Blum K, Baumbach J, Azevedo V. Barh D, et al. Among authors: kumar a. Integr Biol (Camb). 2013 Mar;5(3):495-509. doi: 10.1039/c2ib20206a. Integr Biol (Camb). 2013. PMID: 23288366
A novel comparative genomics analysis for common drug and vaccine targets in Corynebacterium pseudotuberculosis and other CMN group of human pathogens.
Barh D, Jain N, Tiwari S, Parida BP, D'Afonseca V, Li L, Ali A, Santos AR, Guimarães LC, de Castro Soares S, Miyoshi A, Bhattacharjee A, Misra AN, Silva A, Kumar A, Azevedo V. Barh D, et al. Among authors: kumar a. Chem Biol Drug Des. 2011 Jul;78(1):73-84. doi: 10.1111/j.1747-0285.2011.01118.x. Epub 2011 May 25. Chem Biol Drug Des. 2011. PMID: 21443692
Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds.
Barh D, Barve N, Gupta K, Chandra S, Jain N, Tiwari S, Leon-Sicairos N, Canizalez-Roman A, dos Santos AR, Hassan SS, Almeida S, Ramos RT, de Abreu VA, Carneiro AR, Soares Sde C, Castro TL, Miyoshi A, Silva A, Kumar A, Misra AN, Blum K, Braverman ER, Azevedo V. Barh D, et al. Among authors: kumar a. PLoS One. 2013;8(1):e52773. doi: 10.1371/journal.pone.0052773. Epub 2013 Jan 30. PLoS One. 2013. PMID: 23382822 Free PMC article.
miRegulome: a knowledge-base of miRNA regulomics and analysis.
Barh D, Kamapantula B, Jain N, Nalluri J, Bhattacharya A, Juneja L, Barve N, Tiwari S, Miyoshi A, Azevedo V, Blum K, Kumar A, Silva A, Ghosh P. Barh D, et al. Among authors: kumar a. Sci Rep. 2015 Aug 5;5:12832. doi: 10.1038/srep12832. Sci Rep. 2015. PMID: 26243198 Free PMC article.
Whole-genome sequence of Corynebacterium pseudotuberculosis strain Cp162, isolated from camel.
Hassan SS, Schneider MP, Ramos RT, Carneiro AR, Ranieri A, Guimarães LC, Ali A, Bakhtiar SM, Pereira Ude P, dos Santos AR, Soares Sde C, Dorella F, Pinto AC, Ribeiro D, Barbosa MS, Almeida S, Abreu V, Aburjaile F, Fiaux K, Barbosa E, Diniz C, Rocha FS, Saxena R, Tiwari S, Zambare V, Ghosh P, Pacheco LG, Dowson CG, Kumar A, Barh D, Miyoshi A, Azevedo V, Silva A. Hassan SS, et al. Among authors: kumar a. J Bacteriol. 2012 Oct;194(20):5718-9. doi: 10.1128/JB.01373-12. J Bacteriol. 2012. PMID: 23012291 Free PMC article.
A novel strategy of epitope design in Neisseria gonorrhoeae.
Barh D, Misra AN, Kumar A, Vasco A. Barh D, et al. Among authors: kumar a. Bioinformation. 2010 Jul 6;5(2):77-85. doi: 10.6026/97320630005077. Bioinformation. 2010. PMID: 21346868 Free PMC article.
Due to availability of several host and pathogen genomes and numerous tools for in silico prediction of effective B-cell and T-cell epitopes; recent trend of vaccine designing has been shifted to peptide or epitope based vaccines that are more specific, safe, and easy to produce. …
Due to availability of several host and pathogen genomes and numerous tools for in silico prediction of effective B-cell and T-cell epitopes …
A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer.
Barh D, Jain N, Tiwari S, Field JK, Padin-Iruegas E, Ruibal A, López R, Herranz M, Bhattacharya A, Juneja L, Viero C, Silva A, Miyoshi A, Kumar A, Blum K, Azevedo V, Ghosh P, Liloglou T. Barh D, et al. Among authors: kumar a. BMC Genomics. 2013;14 Suppl 6(Suppl 6):S5. doi: 10.1186/1471-2164-14-S6-S5. Epub 2013 Oct 25. BMC Genomics. 2013. PMID: 24564251 Free PMC article.
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