Ahmed NS - Search Results

1

Design of novel β-carboline derivatives with pendant 5-bromothienyl and their evaluation as phosphodiesterase-5 inhibitors.

El-Gamil DS, Ahmed NS, Gary BD, Piazza GA, Engel M, Hartmann RW, Abadi AH. El-Gamil DS, et al. Among authors: ahmed ns. Arch Pharm (Weinheim). 2013 Jan;346(1):23-33. doi: 10.1002/ardp.201200334. Arch Pharm (Weinheim). 2013. PMID: 23307609 Free PMC article.

2

Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents.

Abadi AH, Abouel-Ella DA, Ahmed NS, Gary BD, Thaiparambil JT, Tinsley HN, Keeton AB, Piazza GA. Abadi AH, et al. Among authors: ahmed ns. Arzneimittelforschung. 2009;59(8):415-21. doi: 10.1055/s-0031-1296417. Arzneimittelforschung. 2009. PMID: 19813465 Free PMC article.

3

A novel access to arylated and heteroarylated beta-carboline based PDE5 inhibitors.

Ahmed NS, Gary BD, Piazza GA, Tinsley HN, Laufer S, Abadi AH. Ahmed NS, et al. Med Chem. 2010 Nov;6(6):374-87. doi: 10.2174/157340610793563992. Med Chem. 2010. PMID: 21054274 Free PMC article.

4

Design, synthesis and structure-activity relationship of functionalized tetrahydro-β-carboline derivatives as novel PDE5 inhibitors.

Ahmed NS, Gary BD, Tinsley HN, Piazza GA, Laufer S, Abadi AH. Ahmed NS, et al. Arch Pharm (Weinheim). 2011 Mar;344(3):149-57. doi: 10.1002/ardp.201000236. Epub 2010 Dec 22. Arch Pharm (Weinheim). 2011. PMID: 21384413 Free PMC article.

5

Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives.

Ahmed NS, Ali AH, El-Nashar SM, Gary BD, Fajardo AM, Tinsley HN, Piazza GA, Negri M, Abadi AH. Ahmed NS, et al. Eur J Med Chem. 2012 Nov;57:329-43. doi: 10.1016/j.ejmech.2012.09.029. Epub 2012 Sep 29. Eur J Med Chem. 2012. PMID: 23117589 Free PMC article.

6

Discovery of a novel series of tetrahydro-β-carbolines inducing autophagic cell death in human metastatic melanoma.

Ahmed NS, Elgendy M, Laufer S, Abadi AH. Ahmed NS, et al. Arch Pharm (Weinheim). 2014 Jun;347(6):398-406. doi: 10.1002/ardp.201300437. Epub 2014 Mar 20. Arch Pharm (Weinheim). 2014. PMID: 24652680

7

Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism.

Ahmed NS, Elghazawy NH, ElHady AK, Engel M, Hartmann RW, Abadi AH. Ahmed NS, et al. Eur J Med Chem. 2016 Apr 13;112:171-179. doi: 10.1016/j.ejmech.2016.02.026. Epub 2016 Feb 9. Eur J Med Chem. 2016. PMID: 26896706

8

Design and synthesis of novel flexible ester-containing analogs of tamoxifen and their evaluation as anticancer agents.

Elghazawy NH, Engel M, Hartmann RW, Hamed MM, Ahmed NS, Abadi AH. Elghazawy NH, et al. Among authors: ahmed ns. Future Med Chem. 2016;8(3):249-56. doi: 10.4155/fmc.15.181. Epub 2016 Feb 22. Future Med Chem. 2016. PMID: 26898104

9

Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors.

Elhady AK, Sigler SC, Noureldin N, Canzoneri JC, Ahmed NS, Piazza GA, Abadi AH. Elhady AK, et al. Among authors: ahmed ns. Sci Pharm. 2015 Sep 26;84(3):428-446. doi: 10.3390/scipharm84030428. Sci Pharm. 2015. PMID: 28117310 Free PMC article.

10

Expanding the chemical space of anti-HCV NS5A inhibitors by stereochemical exchange and peptidomimetic approaches.

Ramsis TM, Abdel Karim SE, Vassilaki N, Frakolaki E, Kamal AAM, Zoidis G, Ahmed NS, Abadi AH. Ramsis TM, et al. Among authors: ahmed ns. Arch Pharm (Weinheim). 2018 Jul;351(7):e1800017. doi: 10.1002/ardp.201800017. Epub 2018 May 25. Arch Pharm (Weinheim). 2018. PMID: 29799645

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