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Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation.
Delbroek L, Van Kolen K, Steegmans L, da Cunha R, Mandemakers W, Daneels G, De Bock PJ, Zhang J, Gevaert K, De Strooper B, Alessi DR, Verstreken P, Moechars DW. Delbroek L, et al. Among authors: de bock pj, de strooper b. J Pharm Biomed Anal. 2013 Mar 25;76:49-58. doi: 10.1016/j.jpba.2012.12.002. Epub 2012 Dec 16. J Pharm Biomed Anal. 2013. PMID: 23313773 Free PMC article.
LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism.
Arranz AM, Delbroek L, Van Kolen K, Guimarães MR, Mandemakers W, Daneels G, Matta S, Calafate S, Shaban H, Baatsen P, De Bock PJ, Gevaert K, Vanden Berghe P, Verstreken P, De Strooper B, Moechars D. Arranz AM, et al. Among authors: de bock pj. J Cell Sci. 2015 Feb 1;128(3):541–52. doi: 10.1242/jcs.158196. J Cell Sci. 2015. PMID: 25501810
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.
Matta S, Van Kolen K, da Cunha R, van den Bogaart G, Mandemakers W, Miskiewicz K, De Bock PJ, Morais VA, Vilain S, Haddad D, Delbroek L, Swerts J, Chávez-Gutiérrez L, Esposito G, Daneels G, Karran E, Holt M, Gevaert K, Moechars DW, De Strooper B, Verstreken P. Matta S, et al. Among authors: de bock pj, de strooper b. Neuron. 2012 Sep 20;75(6):1008-21. doi: 10.1016/j.neuron.2012.08.022. Neuron. 2012. PMID: 22998870 Free article.
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.
Van Damme P, Evjenth R, Foyn H, Demeyer K, De Bock PJ, Lillehaug JR, Vandekerckhove J, Arnesen T, Gevaert K. Van Damme P, et al. Among authors: de bock pj. Mol Cell Proteomics. 2011 May;10(5):M110.004580. doi: 10.1074/mcp.M110.004580. Epub 2011 Mar 7. Mol Cell Proteomics. 2011. PMID: 21383206 Free PMC article.
Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs.
Van Damme P, Maurer-Stroh S, Plasman K, Van Durme J, Colaert N, Timmerman E, De Bock PJ, Goethals M, Rousseau F, Schymkowitz J, Vandekerckhove J, Gevaert K. Van Damme P, et al. Among authors: de bock pj. Mol Cell Proteomics. 2009 Feb;8(2):258-72. doi: 10.1074/mcp.M800060-MCP200. Epub 2008 Oct 3. Mol Cell Proteomics. 2009. PMID: 18836177 Free article.
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