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Page 1
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CV, Van de Casteele M, German MS, Bouwens L, Heimberg H. Baeyens L, et al. Among authors: van de casteele m, de groef s. Nat Biotechnol. 2014 Jan;32(1):76-83. doi: 10.1038/nbt.2747. Epub 2013 Nov 17. Nat Biotechnol. 2014. Retraction in: Nat Biotechnol. 2020 Mar;38(3):374. doi: 10.1038/s41587-020-0426-2 PMID: 24240391 Free PMC article. Retracted.
Partial duct ligation: β-cell proliferation and beyond.
Van de Casteele M, Leuckx G, Cai Y, Yuchi Y, Coppens V, De Groef S, Van Gassen N, Baeyens L, Heremans Y, Wright CV, Heimberg H. Van de Casteele M, et al. Among authors: de groef s, van gassen n. Diabetes. 2014 Aug;63(8):2567-77. doi: 10.2337/db13-0831. Diabetes. 2014. PMID: 25060885 No abstract available.
Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CVE, Van de Casteele M, German MS, Bouwens L, Heimberg H. Baeyens L, et al. Among authors: van de casteele m, de groef s. Nat Biotechnol. 2020 Mar;38(3):374. doi: 10.1038/s41587-020-0426-2. Nat Biotechnol. 2020. PMID: 32066957 Free PMC article.
Estrogen Receptor α Regulates β-Cell Formation During Pancreas Development and Following Injury.
Yuchi Y, Cai Y, Legein B, De Groef S, Leuckx G, Coppens V, Van Overmeire E, Staels W, De Leu N, Martens G, Van Ginderachter JA, Heimberg H, Van de Casteele M. Yuchi Y, et al. Among authors: van de casteele m, de groef s, van ginderachter ja, van overmeire e, de leu n. Diabetes. 2015 Sep;64(9):3218-28. doi: 10.2337/db14-1798. Epub 2015 May 26. Diabetes. 2015. PMID: 26015547
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.
Xu X, D'Hoker J, Stangé G, Bonné S, De Leu N, Xiao X, Van de Casteele M, Mellitzer G, Ling Z, Pipeleers D, Bouwens L, Scharfmann R, Gradwohl G, Heimberg H. Xu X, et al. Among authors: van de casteele m, de leu n. Cell. 2008 Jan 25;132(2):197-207. doi: 10.1016/j.cell.2007.12.015. Cell. 2008. PMID: 18243096 Free article.
Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program.
van Arensbergen J, García-Hurtado J, Moran I, Maestro MA, Xu X, Van de Casteele M, Skoudy AL, Palassini M, Heimberg H, Ferrer J. van Arensbergen J, et al. Among authors: van de casteele m. Genome Res. 2010 Jun;20(6):722-32. doi: 10.1101/gr.101709.109. Epub 2010 Apr 15. Genome Res. 2010. PMID: 20395405 Free PMC article.
Sources of beta cells inside the pancreas.
De Groef S, Staels W, Van Gassen N, Lemper M, Yuchi Y, Sojoodi M, Bussche L, Heremans Y, Leuckx G, De Leu N, Van de Casteele M, Baeyens L, Heimberg H. De Groef S, et al. Among authors: van de casteele m, van gassen n, de leu n. Diabetologia. 2016 Sep;59(9):1834-7. doi: 10.1007/s00125-016-3879-6. Epub 2016 Apr 6. Diabetologia. 2016. PMID: 27053238 Review.
Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation.
De Groef S, Leuckx G, Van Gassen N, Staels W, Cai Y, Yuchi Y, Coppens V, De Leu N, Heremans Y, Baeyens L, Van de Casteele M, Heimberg H. De Groef S, et al. Among authors: van de casteele m, van gassen n, de leu n. J Vis Exp. 2015 Aug 7;(102):e52765. doi: 10.3791/52765. J Vis Exp. 2015. PMID: 26273954 Free PMC article.
Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas.
Van Gassen N, Van Overmeire E, Leuckx G, Heremans Y, De Groef S, Cai Y, Elkrim Y, Gysemans C, Stijlemans B, Van de Casteele M, De Baetselier P, De Leu N, Heimberg H, Van Ginderachter JA. Van Gassen N, et al. Among authors: van de casteele m, de groef s, van ginderachter ja, de baetselier p, van overmeire e, de leu n. Eur J Immunol. 2015 May;45(5):1482-93. doi: 10.1002/eji.201445013. Epub 2015 Mar 19. Eur J Immunol. 2015. PMID: 25645754 Free article.
91 results