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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Marsboom G, et al. Circ Res. 2012 May 25;110(11):1484-97. doi: 10.1161/CIRCRESAHA.111.263848. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511751 Free PMC article.
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Thébaud B, Husain AN, Cipriani N, Rehman J. Archer SL, et al. Among authors: marsboom g. Circulation. 2010 Jun 22;121(24):2661-71. doi: 10.1161/CIRCULATIONAHA.109.916098. Epub 2010 Jun 7. Circulation. 2010. PMID: 20529999 Free PMC article.
Epigenetic mechanisms of pulmonary hypertension.
Kim GH, Ryan JJ, Marsboom G, Archer SL. Kim GH, et al. Among authors: marsboom g. Pulm Circ. 2011 Jul-Sep;1(3):347-56. doi: 10.4103/2045-8932.87300. Pulm Circ. 2011. PMID: 22140624 Free PMC article.
37 results