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Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.
Storti P, Bolzoni M, Donofrio G, Airoldi I, Guasco D, Toscani D, Martella E, Lazzaretti M, Mancini C, Agnelli L, Patrene K, Maïga S, Franceschi V, Colla S, Anderson J, Neri A, Amiot M, Aversa F, Roodman GD, Giuliani N. Storti P, et al. Among authors: patrene k. Leukemia. 2013 Aug;27(8):1697-706. doi: 10.1038/leu.2013.24. Epub 2013 Jan 24. Leukemia. 2013. PMID: 23344526
Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.
D'Souza S, del Prete D, Jin S, Sun Q, Huston AJ, Kostov FE, Sammut B, Hong CS, Anderson JL, Patrene KD, Yu S, Velu CS, Xiao G, Grimes HL, Roodman GD, Galson DL. D'Souza S, et al. Among authors: patrene kd. Blood. 2011 Dec 22;118(26):6871-80. doi: 10.1182/blood-2011-04-346775. Epub 2011 Oct 31. Blood. 2011. PMID: 22042697 Free PMC article.
Osteoclasts are important for bone angiogenesis.
Cackowski FC, Anderson JL, Patrene KD, Choksi RJ, Shapiro SD, Windle JJ, Blair HC, Roodman GD. Cackowski FC, et al. Among authors: patrene kd. Blood. 2010 Jan 7;115(1):140-9. doi: 10.1182/blood-2009-08-237628. Epub 2009 Nov 3. Blood. 2010. PMID: 19887675 Free PMC article.
ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivo.
Ishizuka H, García-Palacios V, Lu G, Subler MA, Zhang H, Boykin CS, Choi SJ, Zhao L, Patrene K, Galson DL, Blair HC, Hadi TM, Windle JJ, Kurihara N, Roodman GD. Ishizuka H, et al. Among authors: patrene k. J Bone Miner Res. 2011 Jan;26(1):169-81. doi: 10.1002/jbmr.199. J Bone Miner Res. 2011. PMID: 20683884 Free PMC article.
Activating transcription factor 4 regulates osteoclast differentiation in mice.
Cao H, Yu S, Yao Z, Galson DL, Jiang Y, Zhang X, Fan J, Lu B, Guan Y, Luo M, Lai Y, Zhu Y, Kurihara N, Patrene K, Roodman GD, Xiao G. Cao H, et al. Among authors: patrene k. J Clin Invest. 2010 Aug;120(8):2755-66. doi: 10.1172/JCI42106. Epub 2010 Jul 12. J Clin Invest. 2010. PMID: 20628199 Free PMC article.
40 results