Helleday T - Search Results

1

Castration therapy results in decreased Ku70 levels in prostate cancer.

Al-Ubaidi FL, Schultz N, Loseva O, Egevad L, Granfors T, Helleday T. Al-Ubaidi FL, et al. Among authors: helleday t. Clin Cancer Res. 2013 Mar 15;19(6):1547-56. doi: 10.1158/1078-0432.CCR-12-2795. Epub 2013 Jan 24. Clin Cancer Res. 2013. PMID: 23349316

2

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells.

Lundin C, Erixon K, Arnaudeau C, Schultz N, Jenssen D, Meuth M, Helleday T. Lundin C, et al. Among authors: helleday t. Mol Cell Biol. 2002 Aug;22(16):5869-78. doi: 10.1128/MCB.22.16.5869-5878.2002. Mol Cell Biol. 2002. PMID: 12138197 Free PMC article.

3

RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.

Lundin C, Schultz N, Arnaudeau C, Mohindra A, Hansen LT, Helleday T. Lundin C, et al. Among authors: helleday t. J Mol Biol. 2003 May 2;328(3):521-35. doi: 10.1016/s0022-2836(03)00313-9. J Mol Biol. 2003. PMID: 12706714

4

Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination.

Schultz N, Lopez E, Saleh-Gohari N, Helleday T. Schultz N, et al. Among authors: helleday t. Nucleic Acids Res. 2003 Sep 1;31(17):4959-64. doi: 10.1093/nar/gkg703. Nucleic Acids Res. 2003. PMID: 12930944 Free PMC article.

5

p53 protects from replication-associated DNA double-strand breaks in mammalian cells.

Kumari A, Schultz N, Helleday T. Kumari A, et al. Among authors: helleday t. Oncogene. 2004 Mar 25;23(13):2324-9. doi: 10.1038/sj.onc.1207379. Oncogene. 2004. PMID: 14743204

6

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.

Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, Kyle S, Meuth M, Curtin NJ, Helleday T. Bryant HE, et al. Among authors: helleday t. Nature. 2005 Apr 14;434(7035):913-7. doi: 10.1038/nature03443. Nature. 2005. PMID: 15829966 Free article.

7

Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks.

Saleh-Gohari N, Bryant HE, Schultz N, Parker KM, Cassel TN, Helleday T. Saleh-Gohari N, et al. Among authors: helleday t. Mol Cell Biol. 2005 Aug;25(16):7158-69. doi: 10.1128/MCB.25.16.7158-7169.2005. Mol Cell Biol. 2005. PMID: 16055725 Free PMC article.

8

Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy.

Helleday T, Bryant HE, Schultz N. Helleday T, et al. Cell Cycle. 2005 Sep;4(9):1176-8. doi: 10.4161/cc.4.9.2031. Epub 2005 Sep 12. Cell Cycle. 2005. PMID: 16123586 Review.

9

Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer susceptibility.

Lindh AR, Rafii S, Schultz N, Cox A, Helleday T. Lindh AR, et al. Among authors: helleday t. Hum Mol Genet. 2006 Apr 1;15(7):1217-24. doi: 10.1093/hmg/ddl037. Epub 2006 Feb 27. Hum Mol Genet. 2006. PMID: 16505003

10

RAD51C (RAD51L2) is involved in maintaining centrosome number in mitosis.

Renglin Lindh A, Schultz N, Saleh-Gohari N, Helleday T. Renglin Lindh A, et al. Among authors: helleday t. Cytogenet Genome Res. 2007;116(1-2):38-45. doi: 10.1159/000097416. Cytogenet Genome Res. 2007. PMID: 17268176

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